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Metformin's role in causing or exacerbating neuropathy?

 
 
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Old 05-17-2023, 07:39 PM #1
newToSFN newToSFN is offline
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Join Date: Nov 2019
Location: United States
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newToSFN newToSFN is offline
Junior Member
 
Join Date: Nov 2019
Location: United States
Posts: 51
3 yr Member
Default Metformin's role in causing or exacerbating neuropathy?
Aside from lowering vitamin B12 levels and blocking the thiamine transporter, can metformin cause, contribute to, or exacerbate neuropathy via any other mechanism?

Have any of you all (either prediabetic or with diabetes) taken metformin following your SFN diagnosis? Did it exacerbate your neuropathy symptoms (assuming your B12 levels were adequate and sufficient Thiamine intake)?
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b12, levels, metformin, neuropathy, thiamine

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