I have posted on a couple of other neuro sites and had no responses but this looks like a fairly active site, so thanks so much for 'listening'!

Four weeks ago I was diagnosed with Peripheral Neuropathy. At that stage I had had burning/buzzing/icy sensations in my lower legs for about six weeks prior. Initially the burning/buzzing/icy sensations only occurred later in the day, then they became all day. This was when I was diagnosed. Throughout this whole time I have also had extreme fatigue.

At that time my GP ordered a random blood glucose and a B12 test. Both tests came back ‘normal’.

Within a week of diagnosis I started to feel the burning extending above the knees and in patches over my thigh, groin and in my forearms then fingers of right hand and around my lips, right cheek and chin.

I then developed nausea and liver pains one week after diagnosis. I went again to my GP who sent me straight to hospital fearing Guillain Barre, as the parasthaesias had advanced quite quickly since the previous week when he saw me. All my reflexes and muscle strength were good and the hospital sent me home. The nausea lasted eleven days and I felt quite sick and very fatigued throughout that time.

I returned to my doctor again the following week and he referred me to a neurologist who I saw two weeks ago. She took a fairly comprehensive history and again tested muscle strength and reflexes. She ordered lots of blood tests, which I've had done, and an EMG/nerve conduction test which was done this morning and a brain MRI on Monday Sept 3rd.

In the past week I feel that I am becoming more clumsy, tripping and dropping things but of course I have a very reasonable explanation each time it happens and maybe I'm just being hypervigilant and imagining things!!!!!LOL

I've also had some weird symptoms like extreme 'gut' pain episodes and excruciating right ankle pain which came out of the blue and disappeared within three days. Also mentioned to my neurologist that for some months I had been choking on my saliva a few times per week which wasn't normal for me. I have been having strong cramps in my calves (mostly at night) and twitches (fasciculations - I think they are called) in different areas over the past 6-8 weeks. The twitches tend to be over larger areas of muscle than I have ever had before although to date they only last a few minutes each.

I don't know if these seemingly disparate symptoms have any connection to anything........so

.....I am posting to see if any of you 'experts' can cast light on what may be causing all this. Does this progression of symptoms 'fit' anything in your experience related to PN?? Is there hope of an eventual diagnosis of the underlying cause?

Also wanted to ask about the benefit of Lumber Punctures. Have many of you had an LP as a diagnostic tool? Anyone with PN had a negative Lumber Puncture result?

Sorry.....almost finished. If the EMG/NCS is negative does this mean I do not have PN or what is going on?

I guess I just want to be as informed as possible before I next see the neurologist on Sept 12th.