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Old 12-13-2007, 08:39 PM #1
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Alkymst Alkymst is offline
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Location: Pennsylvania
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Alkymst Alkymst is offline
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Join Date: Jan 2007
Location: Pennsylvania
Posts: 231
15 yr Member
Default A potentially new approach to neuropathic pain

I saw this link on the American Pain Foundation website and thought it was worth a thread here. The research is in rodents only so this is nowhere near a treatment but it potentially represents a new avenue to attack neuropathic pain. A group at UCSD School of Medicine has identified a protein LRP1 that may help to ease neuropathic pain by blocking the response of glial cells that support and protect sensory neurons in the peripheral nervous system.

"The UCSD studies show that a form of LRP1 that is present in body fluids such as blood counteracts the activity of inflammatory cytokines, proteins which are involved in developing and sustaining chronic pain states. Cytokines act as messengers to either stimulate or inhibit the immune response, are produced by many cell types including white blood cells present during infection and inflammation."

http://www.newswise.com/articles/view/535944/?sc=dwhp

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