Neuropathy does improve

Idiopathic PN · 02-24-2012, 03:29 PM

Quote:

Originally Posted by mrsD

The thyroid "warning" is based on ONE study on animals only.
It used only ALPHA racemic ALA and not the purified R-lipoic.
So the other portion of the racemic version may be the culprit, but no one knows.

It has never been done on humans or replicated. Replication by other study groups is typically needed before concrete
conclusions can be brought on medical issues.

When any "negative" thing appears in searches of MedLine, all the quality online sites pick it up and repeat it. In this case it has not been proven at all at this time and not in humans.

People on thyroid treatments, should be monitored anyway carefully for changes. So any effects would show up that way.

I am hypo and I take R-lipoic and have noticed no new signs of my hypo that I suffered with before I was diagnosed. In fact my cold intolerance is better!

It is your choice in the end, but consider the decision is based on very little evidence.

I'd take the gabapentin by itself spaced a long way time wise from any mineral supplement. Magnesium is ++ (called divalent) like calcium and iron are and it has shown to reduce gabapentin's absorption in the GI tract. Gabapentin is already not well absorbed under ideal conditions.

Fiber is well known to complex out some drugs. Fiber will prevent thyroid hormone from being absorbed at all!
I would space out fiber as well, away from gabapentin AND thyroid replacement hormones.

Thank you so much Mrs. D!

Sometimes, when the pain is reduced to a tolerable level, I find humor in the schedules of my day. It seems that my day revolves around observing what medicines to take at what time. Please give me your th oughts on my spacing:

1. 5 AM - Synthroid (empty stomach)
2. 6 AM - VB12 - methylcobalamin (empty stomach)
3. 7 AM - Gabapentin, then I i eat breakfast
4. 9 AM - Vitamins and supplements
5. 10 AM - Calcium supplement
6. 2 PM - Gabapentin
7. 4 PM - Calcium supplement (I need to take this 3x a day due to an early sing of osteoporosis)
8. 5 PM - Fiber supplement
9. 7 PM - Gabapentin
10. 9 PM - Fiber supplement (I need to take another fiber before sleeping due to the effect of gabapentin on my BM)

You see Mrs. D, with this spacing, I could not follow the 3x a day for my calcium because I dont know when to squeeze calcium knowing it will affect the gabapentin.

I will try the R-Lipoic Acid.... I will start on the lowest dosage. Can I take it together with my other supplements at 9AM?

May I know what medicine/s are you taking for your neuropathy? Gabapentin is my first medication and I think I will stick to it. My 2nd neuro told me during my last visit that she will consider giving me Cymbalta if my symptoms do not improve. Is this a good combination for neuropathy?

Thank you very much!!! I truly appreciate your generosity of sh aring your time and information.

Idiopathic PN

P.s. I checked the "remember me" box. Thanks again!!!!

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