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Old 04-23-2008, 04:20 PM #31
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I found this and maybe someone else posted but I thought I would again.

Is Vitamin D Insufficiency Associated With Peripheral Neuropathy?

CME Review Article #30

Endocrinologist. 17(6):319-325, November/December 2007.
Carlson, Amanda N. MD *; Kenny, Anne M. MD +
Abstract:
The effects of vitamin D on calcium and phosphate metabolism and bone formation are well studied. For many years, it was thought that the importance of vitamin D was confined to these roles, and the study of this hormone's activity in other tissues was neglected. In recent years, however, there has been a renewed interest among researchers in identifying other target organs for vitamin D, such as the central nervous system. Increasingly, it appears that vitamin D plays a role in nerve growth and maintenance and may have important pharmaceutical applications for treatment of neurodegenerative conditions. This review focuses on our growing understanding of the biology of vitamin D in the brain and the potential pathophysiologic and therapeutic relationships that exist between vitamin D and neuronal dysfunction.

(C) 2007 Lippincott Williams & Wilkins, Inc.
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Old 04-25-2008, 03:09 AM #32
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I was experiencing pain in the joint of my big toe, both left and right foot....in the ball of the foot - *that* joint. I started taking Vit - D because of other considerations but a side effect for me was that that pain went away. If I stop the D it comes back.
Hi thanks for all the replys,its early days yet but I swear the neuropathy is lessening,but maybe im having a few good days,I will mention the gluten test next time I see the doctor. Thanks again Mark
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Old 05-21-2008, 10:13 AM #33
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Hi all, I haven't had much time to post this year but just to let you all know that since taking vitamin d supplements the neuropathy 'seems' to be subsideing... not sure if it's just a lull or whether the severe lack of vitamin d was playing some sort of role in the neuropathy. I am hoping that maybe this info will be of use to others...
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Old 05-21-2008, 10:40 AM #34
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Hi all, I haven't had much time to post this year but just to let you all know that since taking vitamin d supplements the neuropathy 'seems' to be subsideing... not sure if it's just a lull or whether the severe lack of vitamin d was playing some sort of role in the neuropathy. I am hoping that maybe this info will be of use to others...
That's wonderful news! And something we all like to hear. Congrats!
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Old 05-21-2008, 11:11 AM #35
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Lightbulb low D

means low calcium absorption. Low calcium leads to paresthesias and
it might seem like PN.
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Old 05-29-2008, 08:42 AM #36
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means low calcium absorption. Low calcium leads to paresthesias and
it might seem like PN.
Hi there ,when I was taking calcium and Magnesium supplements last year they made all the symptoms much worse, it seems to be pieceing together that vitamin D may be playing a role in it,if you don't have vitamin D does that mean that calcium does not get absorbed and instead goes somewhere else? Does paresthesias cause some sort of axonopathy because my EMG showed that I have some sort of axonopathy...
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Old 05-29-2008, 08:43 AM #37
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That's wonderful news! And something we all like to hear. Congrats!
Thanks jarrett, how are you doing?
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Old 05-29-2008, 09:29 AM #38
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Lightbulb low D

Means that the body will start robbing the bones for calcium.
Typically the system that does this is the parathyroid glands.
They may become overstimulated and create a secondary hyperparathyroidism.
This actually raises serum calcium in many cases.
But hypocalcemia may occur too. It can be very complicated.

Correcting Vit D usually corrects this.

When calcium and magnesium go out of balance, and there is too much calcium or too little, paraesthesias occur.

http://www.emedicine.com/med/topic1118.htm
for hypocalcemia

Not all calcium is aborbed from the GI tract even under ideal conditions.
About 60% is eliminated in the feces.
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Old 05-29-2008, 09:46 AM #39
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Thanks jarrett, how are you doing?
When I sit and think about where I was a year ago... I'm doing really well. And since I quit smoking I've had a huge change in the symptom of burning in the feet. It would seem that many of my symptoms were being caused by smoking. Imagine that. Though if one googles they won't find anything definitive linking smoking to PN. But common sense would dictate it must if PN can be caused by chemical exposures. Look at the list of chemicals contained in cigarettes!
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Old 05-29-2008, 11:42 AM #40
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Originally Posted by mrsd View Post
Means that the body will start robbing the bones for calcium.
Typically the system that does this is the parathyroid glands.
They may become overstimulated and create a secondary hyperparathyroidism.
This actually raises serum calcium in many cases.
But hypocalcemia may occur too. It can be very complicated.

Correcting Vit D usually corrects this.

When calcium and magnesium go out of balance, and there is too much calcium or too little, paraesthesias occur.

http://www.emedicine.com/med/topic1118.htm
for hypocalcemia

Not all calcium is aborbed from the GI tract even under ideal conditions.
About 60% is eliminated in the feces.
Thanks for the info MRSD ,do you know by any chance if vitamin affects dopamine and whether a lack of d means a lack of dopamine in the brain?
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