advertisement
Reply
 
Thread Tools Display Modes
Old 05-29-2008, 11:43 AM #41
Mark._. Mark._. is offline
Member
 
Join Date: Aug 2007
Posts: 108
15 yr Member
Mark._. Mark._. is offline
Member
 
Join Date: Aug 2007
Posts: 108
15 yr Member
Default

Quote:
Originally Posted by jarrett622 View Post
When I sit and think about where I was a year ago... I'm doing really well. And since I quit smoking I've had a huge change in the symptom of burning in the feet. It would seem that many of my symptoms were being caused by smoking. Imagine that. Though if one googles they won't find anything definitive linking smoking to PN. But common sense would dictate it must if PN can be caused by chemical exposures. Look at the list of chemicals contained in cigarettes!
I'm glad to hear that you are doing well and that you have given up smoking. I gave up last year but started again to help a stressfull situation. I am going to try and quit again at some point...
Mark._. is offline   Reply With QuoteReply With Quote

advertisement
Old 05-29-2008, 11:56 AM #42
mrsD's Avatar
mrsD mrsD is offline
Wisest Elder Ever
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb here is what I found:

http://www.oralchelation.com/ingred/VitaminD1.htm
Quote:
Activated vitamin D in the adrenal gland regulates tyrosine hydroxylase, the rate limiting enzyme necessary for the production of dopamine, epinephrine and norepinephrine.

Low vitamin D may contribute to chronic fatigue and depression. (9-10) Seasonal Affective Disorder has been treated successfully with vitamin D. In a recent study covering 30 days of treatment comparing Vitamin D and 2 hour daily use of 'light boxes', depression completely resolved in the D group, but not in the light box group.(11)
Now, tyrosine also has to be provided as a precursor.
and:
Quote:
Mov Disord. 2007 Mar 15;22(4):461-8.Click here to read Links
Vitamin D and Parkinson's disease--a hypothesis.
Newmark HL, Newmark J.

Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA. pnewmark@verizon.net

Parkinson's disease (PD), a common disease of the elderly, is a movement disorder characterized by tremor, akinesia, and loss of postural reflexes, leading to immobility and frequent falls. It results from selective loss (death) of dopaminergic neurons in the substantia nigra region of the brain, largely developed prior to clinical diagnosis, and continuous after diagnosis, despite use of current therapeutic modalities. In PD in the United States the cause and mechanism of continued neuron cell death in the substantia nigra is currently unknown. We hypothesize, based upon several lines of evidence, that documented chronically inadequate vitamin D intake in the United States, particularly in the northern states and particularly in the elderly, is a significant factor in the pathogenesis of PD. This hypothesis implies that dietary aid for prevention and therapy for PD is possible. (c) 2006 Movement Disorder Society.

PMID: 17230473 [PubMed - indexed for MEDLINE]
There are just global effects of low Vit D coming forth in the press and
in research. The Vitamin D Council has many papers.
http://www.vitamindcouncil.org/
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

************************************

.
Weezie looking at petunias 8.25.2017


****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
mrsD is offline   Reply With QuoteReply With Quote
Old 05-29-2008, 12:04 PM #43
NaeNae's Avatar
NaeNae NaeNae is offline
Senior Member
 
Join Date: Jan 2008
Location: The Sticks, Arkansas
Posts: 1,012
15 yr Member
NaeNae NaeNae is offline
Senior Member
NaeNae's Avatar
 
Join Date: Jan 2008
Location: The Sticks, Arkansas
Posts: 1,012
15 yr Member
Default

About 3 months ago my Vit D levels were less than 2, this is the second time this has happened last time they were 8 though, I took 50,000 uints once a week for 8 weeks.....and then I got kidney stones! Sheesh.
__________________


Renee

One's dignity may be assaulted, vandalized and cruelly mocked, but cannot be taken away unless it is surrendered.
NaeNae is offline   Reply With QuoteReply With Quote
Old 06-02-2008, 09:16 AM #44
Greg Greg is offline
Junior Member
 
Join Date: Jun 2008
Posts: 11
15 yr Member
Greg Greg is offline
Junior Member
 
Join Date: Jun 2008
Posts: 11
15 yr Member
Default

I have been reading about Vit D deficiencies and wondering if there may be a connection with my "idiopathic small fiber PN". Although I did have a skin punch biopsy that showed small fiber abnormalities in my hip and ankle. I wonder if this is still a possibility? I do have decreasing bone density in my painful toes. And I'm only 31.

Thanks everybody for the good info.
Greg is offline   Reply With QuoteReply With Quote
Old 06-02-2008, 04:22 PM #45
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default My opinion--

--just an opinion, though I like to think it's an informed one--is that Vitamin D deficiency alone will not result in peripheral neuropathy, particularly small-fiber neuropathy, although Vitamin D deficiency may result in calcium malabsorption, and low calcium levels to lead to parasthesas ("strange sensations") in nerve--tingling, stinging and the like.

If one is low in Vitamin D--and one certainly can be, especially in higher latitudes during colder times of the year--a thorough work-up for other vitamin/mineral malabsorption should be done: B12, B6, Calcium, Magnesium--especially if there are neurological symptoms. Some deficiencies of this type--especially of the B-vitamins--can lead to neuropathy, and there is also the possibility of gastrointestinal malabsorption syndromes such as IBS, Crohn's, or celiac/gluten sensitivity. The latter two, inasmuch as they are autoimmune in nature, can result in neuropathy themselves, through antibody cross-reaction with nerve epitopes.
glenntaj is offline   Reply With QuoteReply With Quote
Old 06-04-2008, 09:03 PM #46
Mark._. Mark._. is offline
Member
 
Join Date: Aug 2007
Posts: 108
15 yr Member
Mark._. Mark._. is offline
Member
 
Join Date: Aug 2007
Posts: 108
15 yr Member
Default

Quote:
Originally Posted by glenntaj View Post
--just an opinion, though I like to think it's an informed one--is that Vitamin D deficiency alone will not result in peripheral neuropathy, particularly small-fiber neuropathy, although Vitamin D deficiency may result in calcium malabsorption, and low calcium levels to lead to parasthesas ("strange sensations") in nerve--tingling, stinging and the like.

If one is low in Vitamin D--and one certainly can be, especially in higher latitudes during colder times of the year--a thorough work-up for other vitamin/mineral malabsorption should be done: B12, B6, Calcium, Magnesium--especially if there are neurological symptoms. Some deficiencies of this type--especially of the B-vitamins--can lead to neuropathy, and there is also the possibility of gastrointestinal malabsorption syndromes such as IBS, Crohn's, or celiac/gluten sensitivity. The latter two, inasmuch as they are autoimmune in nature, can result in neuropathy themselves, through antibody cross-reaction with nerve epitopes.
All I can say is that I really hope this thread helps some others out there that are suffering because I have to say my symptoms are subsiding big time and it must be down to the vitamin D levels.... if you read back through some of my posts I list my symptoms,they were getting pretty bad,not half as bad as some on here,and I really do feel for those people and what they have to endure,I just hope that this will help someone somewhere get to the root of their problem......
Mark._. is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Curious (06-04-2008)
Old 06-04-2008, 09:06 PM #47
Mark._. Mark._. is offline
Member
 
Join Date: Aug 2007
Posts: 108
15 yr Member
Mark._. Mark._. is offline
Member
 
Join Date: Aug 2007
Posts: 108
15 yr Member
Default

Quote:
Originally Posted by Greg View Post
I have been reading about Vit D deficiencies and wondering if there may be a connection with my "idiopathic small fiber PN". Although I did have a skin punch biopsy that showed small fiber abnormalities in my hip and ankle. I wonder if this is still a possibility? I do have decreasing bone density in my painful toes. And I'm only 31.

Thanks everybody for the good info.

Greg,get all your vitamin levels checked..... they checked mine but obviously didn't bother with D,they only checked when I went to the doctors for something totally unrelated,it's well worth getting D levels checked...
Mark._. is offline   Reply With QuoteReply With Quote
Old 06-05-2008, 08:23 AM #48
mrsD's Avatar
mrsD mrsD is offline
Wisest Elder Ever
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb Vit D and others too...

Please read this :
www.bruceames.org

People all vary in how they utilize nutrients. Drug use can also lower nutrients in the body (this is how many side effects manifest).

This new DNA test is almost here:

http://neurotalk.psychcentral.com/thread17913.html

We are not all identical in how our bodies function.

Vitamin levels are sometimes misleading. They may show only what is in the serum and not what is being used
within the cells. The new Vitamin testing involves genetic flaws in vitamin use, and are not affected
by what you are taking. I think this new testing is very exciting, and may provide an increased quality of
life for many people plagued with vague and idiopathic or hard to diagnose conditions.

Most misleading are levels for some of the Bs and magnesium. Right now we don't have long term data on
the Vit D issue, but it is looking like we can trust those blood levels so far.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

************************************

.
Weezie looking at petunias 8.25.2017


****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.

Last edited by mrsD; 06-05-2008 at 09:04 AM.
mrsD is offline   Reply With QuoteReply With Quote
Old 06-09-2008, 02:24 PM #49
Greg Greg is offline
Junior Member
 
Join Date: Jun 2008
Posts: 11
15 yr Member
Greg Greg is offline
Junior Member
 
Join Date: Jun 2008
Posts: 11
15 yr Member
Default

Thanks for the advice Mark and Glenntaj. I have been tested for several deficiencies, but not D. I'll get that knocked out in 2 weeks at my next visit.

Sounds promising Mrs.D. I've always been curious in regards to B12, how serum levels can be the ultimate gauge when it's not the "end of the line", so to speak, of the absoprtion and utilization process.
Greg is offline   Reply With QuoteReply With Quote
Old 03-17-2010, 10:57 PM #50
okthen okthen is offline
New Member
 
Join Date: Mar 2010
Posts: 1
10 yr Member
okthen okthen is offline
New Member
 
Join Date: Mar 2010
Posts: 1
10 yr Member
Default Ouch

I have not read through much of anything in here yet, but have to say that I am hurting like I have not hurt in months...maybe 6? I have changed nothing and have only increased my decreased dilaudid intake. The last two days have resulted in a new 10 on the 1-10...all this in the face of great things going on personally AND with new hope of pain relief though topical mixes from San Ysidro Pharmacy in Santa Barbara, County. Need help. Need D info. Right hand is becoming useless at times (even doing this!?). Would easily trade some finger for a few days p/ mo relief.

Thanks and sorry for the gloom.
okthen is offline   Reply With QuoteReply With Quote
Reply


Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
B-12 AND Vitamin D Deficiency Jon1260 Vitamins, Nutrients, Herbs and Supplements 8 11-05-2010 12:53 PM
Approaches to vitamin B12 deficiency lou_lou Parkinson's Disease 0 06-17-2007 10:43 PM
Vitamin B12 deficiency Alye Vitamins, Nutrients, Herbs and Supplements 28 06-02-2007 11:46 AM
Vitamin B12 Deficiency / Alzheimers jccgf Alzheimer's Disease 8 10-02-2006 05:58 PM
Vitamin D Deficiency always-aching Vitamins, Nutrients, Herbs and Supplements 4 09-22-2006 07:50 PM


All times are GMT -5. The time now is 02:51 PM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.