[dahlek]

Mrs D? This first one I'd love your comments on? Sounded solid at the start but going to 'referred sites'...well, got a but iffy.
http://www.medicalnewstoday.com:80/articles/109070.php
This caught my attention because of a 'reference' to an 'immune' drip...Got no more out of this all than 'Make an Appointment'... Sounded snake oily to me.. but...you know hope springs eternal?

Others of interest are:
THIS ONE IS GOOD!!!!:
http://www.medicalnewstoday.com/articles/109168.php

This one might want to be in the 'stickies' if you all think so:
http://www.ccjm.org/PDFFILES/Chemali1_05.pdf

Happy reading! - j

[mrsD]

in certainly not new. Here we used to call them Meyer's cocktails.

The holistic MDs at our teaching facilities at Wayne State have been using them for years. I suppose some changes have been made in contents. Like using a newer more bioavailable form for some of the vitamins.

The beauty of them is that they give good magnesium doses without the diarrhea, and of course the glutathione has to be done IV, since you cannot swallow it.

These IVs tend to be very expensive, and also there were some problems with compounding pharmacies screwing up doses. I recall some HoooHaa about that a while ago.

People with malabsorption issues, or genetic errors, or who seem resistant to oral nutrient supplements for some reason, do well on the IVs. But it is a personal choice.

[mrsD]

this is a cholesterol compound?

I'll look into it more tomorrow. But that is ironic...fill people up with statins
to get rid of cholesterol (and cause PN) and then give them a cholesterol based drug to fix them. The drug companies should just LOVE that.

But if it turns out to work, it will definitely be a GodSend for many.
(After 2010 we won't see much about statins anymore anyway...that is when
the last patents expire).

http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Since it was recently published that statins cause mitochondrial damage, and so do chemo drugs...
this looks promising.

[dahlek]

All this all can be both a blessing and a curse at the same time.
All in all, a lot of this relates to US PN'ers and we do have to keep up on this stuffs. How it's actually APPLIED to us...if we are lucky enough in our lifetimes to benefit from it? Well, all the better that we know of it before the 'SALESMEN'! You all know what I mean if you've spent as much time in doc's offices as I have!
On ward and all that. More comments and ruminations are appreciated. - j

[mrsD]

I was looking around today and found this example:

ABT-627:
http://www.ncbi.nlm.nih.gov/pubmed/10657544?ordinalpos=1&itool=EntrezSystem2.PEntrez. Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.P ubmed_Discovery_RA&linkpos=4&log$=relatedarticles& logdbfrom=pubmed
This drug was brought to market finally--- by Abbott as Xinlay and FDA
did not approve.

If you want to follow it on Google--the press releases-- you can see.

So we many find papers, press releases showing promise for pain...but then we
never see them arrive. In this case the drug was decided as a prostate cancer
drug! (bone pain).

I remember memantine (Namenda) getting glowing reports in Europe in the late 90's on our old old board at "you know where".... everyone thought it
would work for PN here, but it is rarely if ever prescribed. I haven't seen one person recently using it for that.
http://212.17.200.140/pr02.htm

Why hasn't this happened here? It could be used off label, since it is only approved here for Alzheimer's.
Why haven't some neurologists offered this off label here to diabetics?
We never see it --- NEVER.

[echoes long ago]

i have been wondering the same thing while reading all of these promising developements in pain and regeneration over the last 5 years.