Is it possible for Lyrica to quit working?

It just seems as if I'm feeling much more pain now than I did about 4 months ago. We are trying to move and it is really getting hard for me to get around. I was taking 375 mg a day and the dose of hydrocodone is the 500 mg. dosage. I find I cannot even begin to think of missing a pill and even then it doesn't do a whole lot for the pain. I know my body has probably become immune to the hydrocodone as I have been having to take it since the breaks in the sacrum and pelvis happened
and that has been almost a year. Eyes are really bad because of that. But I was thinking today and wondered if it is possible to become immune to the Lyrica also. Thanks for any info.

Billye

It's totally normal to build up resistance to hydrocodone and need ever increasing doses for the same amount of relief. I went from 1 to 4 Vicodin tabs over an eight month period before my Dr switched me to oxycodone. Plan is when/if I build resistance to switch back to hydro.

I also thought Lyrica had stopped working for me at 600 mg a day so I started cutting back 75 mg a week till I was down to 300 mg and realized it was working good, my pain had just increased. I worked my way back up to 450 mg and it seems to be doing good for me now.

Hang in there.

I thought this happened to me. When they increased my lyrica my pain level seemed to not go down, infact it seemed to rise. My pain clinic dr. seemed to think I was nuts when I asked it my pain could have gotten worse. (I'm like we don't even know what is causeing the pain, how can we know if it could get worse!) But he wouldn't do anything with my drug levels. IDK. That prompts my question how much lyrica are you allowed to take daily?

.........so I started cutting back 75 mg a week till I was down to 300 mg and realized it was working good, my pain had just increased..........

Billye,
This is a very good possibility.
Although you could be building a tolerance for the Lyrica,
as any of us can do that with many meds after a while.
I don't remember how long you've been on Lyrica, but since its
only been available since the summer of 2005, it can't be a very long while.
I've been taking it since Sept of 2005 and was at the max of 600 mgs/day,
60 days after starting - and still am lucky to have it work for me.
It took 7 years of (eventually) 4200 mgs/day of Neurontin for me
to build up a tolerance, and had to switch.

I do feel after awhile meds don't work as well. I am wondering though if some is cause you are moving and are more active? I must of missed the move decision. Where are you going? Hope you feel better

There are so many medications that weaken bone. Simple Ibuprofen, for example, not to mention Prevacid and other grd medications.

I used to take so much Advil to control pain, until I learned it was weakening my jaw bone and contributing to the infection from my old dental implants.

I started using serrapeptase and while it did not kick in as fast, it works very well. I also use a LOT of methylcobalamin lozenges, generally at least 15 to 10 mg a day.

I had horrible pain before, and don't have it now, so I am inclined to think these things work.

(I used to use twice as much methylcobalamin, but I seem to be gaining on my problem.)

Thanks for the answers. Daniella, we are downsizing and bought a house that is all on the same level. I've sold so many things this week. It's so hard to sell things you paid a lot of money for and get nothing for them. But I am now seeing some bare space around here. I've been cleaning out for about a month or so now and it's slow but I'm getting there. I limp badly when I walk and I don't really know why. No one has been able to tell me. I think it's a combination of things but not really sure.

Daniella, you may be right. I'm twice as active as I was, but it's just slow and labored because of the limp and pain. I get quite frustrated sometimes because my mind wants to do more than this old feeble body can. But my husband tells me I am getting a lot done. My little dogs are totally exhausted today because we have had people in and out all day looking at items we are selling. My once beautiful home is now a wreck and missing a lot of things that I really liked but don't have room for now.

Maybe I'm just pushing myself too much. Thanks all of you for your interest and caring enough to answer this post.

Billye

I too got frustrated and still do with the mind quicker then the body issue. I know for me day in and day out of a lot of activity really adds up and can cause delayed pain. So I may not feel it at the time but later oh my. Do you have time? I know I get eager and want things done but I try to remind myself it is better to take it slow then spend days later in extra pain. When I moved I sold a lot on craigslist. I also found people to help with packing for a very affordable price. I hope the new place helps you and you get comfortable. Is it closer to markets and city things?