[mrsD]

Here is an interesting account from DR. Cohen's website.

http://www.medicationsense.com/artic...ity070508.html

This article suggests Vit E may be protective in people using fluroquinolones. (it was protective in rats so far)

http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Vit E protective in humans:
http://www.ncbi.nlm.nih.gov/pubmed/12540033?ordinalpos=1&itool=EntrezSystem2.PEntrez. Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.P ubmed_Discovery_RA&linkpos=2&log$=relatedarticles& logdbfrom=pubmed

[lefthanded]

Great avatar photos, mrsd!

[dahlek]

I really felt as if you were writing this just for me!

Two months ago I was prescribed Cipro....I asked three times: ARE YOU SURE YOU WANT TO PRESCRIBE THIS TO SOMEONE W/A NEUROPATHY? Yep...
Well, it was a 5 day course and I am now suffering those arthritis-like consequences. I did see my neuro a few weeks ago and asked him if he could write a no-no letter, I'll find out when I see my Gp later this month.
I'd Attributed the arthritis issues to another med I'd been on[notorious for this s/e] but had stopped just before taking the Cipro... and well, it's not gone away, just getting worse.
There is only so much Vit E one can take, you know?
In the meantime? You all can call me 'Grumpy'! - j

[mrsD]

supplements you can try to increase glutathione, without resorting to IV treatments. This site lists them:

http://www.ei-resource.org/treatment...r-supplements/

SAMe will definitely help in the "grump" department, as it also works on mood.

[BEGLET]

sorry - this posted twice

[BEGLET]

Cipro for 5 days during the first year of PN oneset (the PN required leaving work but still had some senosry nerves) - caused C-Diff for six months which then required oral vancol and flagyl to treat for six months and very ill from the combo of meds and infection (of course flagyl a neuro-toxin which I didnt know at the time) to beat and then no sensory nerve conduction at the concousion of treatment... now I'm beginning to wonder - how much did all of these play together to "get" me - was it the cipro, the infection, the other meds? (I'm sure the flagyl did its part) - its never stopped - believed to be genetic - but how much did these little gems contribute... thanks mrs. d for the info - i wonder if years later any actions can help?

[mrsD]

Originally Posted by kmeb

Cipro for 5 days during the first year of PN oneset (the PN required leaving work but still had some senosry nerves) - caused C-Diff for six months which then required oral vancol and flagyl to treat for six months and very ill from the combo of meds and infection (of course flagyl a neuro-toxin which I didnt know at the time) to beat and then no sensory nerve conduction at the concousion of treatment... now I'm beginning to wonder - how much did all of these play together to "get" me - was it the cipro, the infection, the other meds? (I'm sure the flagyl did its part) - its never stopped - believed to be genetic - but how much did these little gems contribute... thanks mrs. d for the info - i wonder if years later any actions can help?

It is really hard to say. If the mitochondria have not died...are just not working properly...the interventions would be useful.

Research into mitochondrial damage, is still very primative.
It is heating up some with autistic research, aging research, etc. We have just seen that statins cause their damage thru mitochondria attack. So do chemo and AIDs drugs.

In your case I would think the drugs were serious players.
It takes many many years for the truth to come out about
drug damage. In the case of fluroquinolones, many of them have been taken off the market. One really terrible one only lasted a couple of weeks--Omniflox-- caused liver failure/death.