I have a post about piroxicam on our Medications forum here.

http://neurotalk.psychcentral.com/showthread.php?t=7391
I think you should read it carefully and the links in it.

Piroxicam does not provide ANY advantage over any other of the traditional
NSAIDs (the older ones) and has a very high risk for bleeding episodes.
In fact it is hardly ever used anymore because of this risk.
Also just because it is once a day dosing, does not mean anything. (doctors sometimes think these are "stronger", but all that is gained is that if you have a reaction it will last all day).

One thing the new drug interactions do not yet mention, is that SSRI's increase bleeding tendencies...and piroxicam is the worst offender of that. Some pharmacies put NSAID warnings on their SSRI patients' bottles now.

So do be careful.

Thiamine has been used for many years and is not my idea per se.
http://www.clinicaltrials.gov/ct/show/NCT00279266
This study should be interesting when completed.
It is unfortunate that its usefulness is eclipsed by drugs like Neurontin and Elavil.

Here is a monograph on Thiamine
http://www.nlm.nih.gov/medlineplus/d...t-thiamin.html

If you want me to look up your drugs for you in the reference I use..concerning
nutrient depletions I can. You can PM me if you need privacy.

Yorkiemom...how many AlkaSeltzer's a day do you take? I only need one dose of two to stop burning. Aspirin in high doses might raise liver enzymes:
In my experience Tylenol is the most common offender.
from http://www.medicinenet.com/liver_blood_tests/page3.htm

Hi Dianna, my PN was caused by prediabetes and low b12, i am curious if you had a Glucose Torence test at the begining of your troubles, or only lately they have thought of giving you the GT test.

You can reverse prediabetes, with tight sugar control and a bit of exercise, i only use to walk up and down the length of the local swimming pool for my exercise as walking on the pavement was just pure murder on my burning feet.

I think it was previuosly thought that you would have to have full blown diabetes and over a long period to do any damage to your nerves which is totaly inncorrect.
I have always been a sweat tooth and loved my beer as well, so i have really no idea how long i had prediabetes before the damage to the nerves showed up.
I give up all high sugary carbs including beer and my feet have improved so much that now i am roughly 98 % free from any burning and lots of the numb areas on my feet have regained their sense of touch again, even i do sneak a high sugar carb every now and again i don't get any burning after it, but i don't push my luck to much, nerves can repair themselves if given the chance to do so.
all the best
Brian

With the old archives gone, I can't easily put my finger on the relevant material. But months ago, Glenntaj posted a study indicating that PN from impaired glucose tolerance was actually reversible with good glycemic control.

On a related note: Have you looked into alpha lipoic acid (ALA)? Studies indicate it can help glycemic control, while in other studies some diabetics have reported rapid relief of their PN with injections of ALA. You can't easily get ALA injections in the U.S., but pill supplements are available at many health food stores.

--that discussed impaired glucose tolerance/pre-diabetic neuropathy extensively, and has some good references:

http://brain.hastypastry.net/forums/...ead.php?t=2122

I also believe I copied the reference list into this thread here:

http://neurotalk.psychcentral.com/sh...1828#post21828

ALA has been used for PN for years in Europe.
Injections of 600 mg 1 or 2 x day are the dosage they've used.
I take "Now" Foods- 600 mg, ALA- daily. I get it from iherb
The drug stores only seem to stock 50 or 100 mg doses.

I am going to print off all these suggestions and reread them again, following the link suggestions, and make some sense out of everything. I have been adding some vitamins (like the B12 over a year ago) a little at a time and I am sure there is more than I need. I appreciate all the information more than you all will ever know.

diana