Having an ANA of 1:128 is strongly suggestive that something is going on, but it is really only a screening test which suggests that further testing should be done. It doesn't tell you what is going on.

As far as the RNP goes, it is really important to use the reference range that comes with your test results, and ignore any other ranges you might come across on the internet. There are many different tests used which all have different ranges, so just go by the test range your lab used. They will be using the correct range for the test they use. That makes your RNP test negative, which is why your doctor disregarded it.

Sorry I don't know anything about helper and supressor cells, but then I really only know about what I have (lupus, antiphospholipid syndrome and sjogrens). Sounds like you need a good doctor continue with testing and monitor you as it can take time to work out what is going on.

Malar rashes are part of lupus, and of course there are many other autoimmune disease than lupus. And, not everyone with lupus has a malar rash, it is only one of the possible symptoms. Nobody has all of them, we all just have our own particular selection.

hth

raglet