[mrsD]

Here is a link to a new paper explaining that B12 levels were found lower in brains with schizophrenia and autism:

http://psychcentral.com/news/2016/01...ism/98153.html

[Lara]

mrsD, I hadn't read your post here before I sent it off in PM. Sorry about that.

Full article here... Totally over my head unfortunately

[Also note limitations with such a small sample size.]

http://journals.plos.org/plosone/art...0146797#sec009

Research Article PLOS ONE
Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia
Published: January 22, 2016
DOI: 10.1371/journal.pone.0146797

[MelodyL]

Originally Posted by mrsD

Here is a link to a new paper explaining that B12 levels were found lower in brains with schizophrenia and autism:

http://psychcentral.com/news/2016/01...ism/98153.html

Hi, I wish I could show this to someone I know. Their son has been diagnosed with Aspergers. Can't bring it up.

I think all diseases and syndromes are caused by heredity and deficiencies in one thing or another. We are meant to have a balanced system. That means not polluting it with processed food and additives. Why are they allowed to be available?. I walk into Dunkin at night to sit with my friends. They are all eating donuts and sugar laden stuff and I just sit there and drink my water. They look at me like I was nuts and I politely say "you know I'm a diabetic and I can't go near any of this'. They all say the same thing 'but can't you cheat once in a while'? I say "Sure, but why would I want to?" They don't get it. I didn't get it when I was young either but I certainly do now.

Why are we bombarded with sugar laden food, sodas, other bad things, tobacco etc. when the known result will be illnesses and diseases? Why? Just so the phamaceutical companies can have a field day with us?

My goodness. I'm just thankful I still grow my sprouts and microgreens. I made a dish tonight that was amazing (without any added sodium). I took bok choy, my pea shoots, my fenugreek, my other microgreens, some onions and garlic, added some orange ginger crystals I get from True Lemon.com and then I did a stir fry (with no salt). Added curry. OMG to die for. I have no idea how but i'll try and upload a photo to this site.

Melody

P.S. I just uploaded the photo of what I cooked tonight. I made it my album cover. The colors of this dish were amazing.

[Kaybaby]

Mrs D,

How does my B12 look?

Thanks so much

VIT B12 BINDING CAPACITY, UNSAT (TRANSCOBALAMIN)
601 L Range 650-1340 (pg/mL)

VITAMIN B12
1189 H Range 200-1100 (pg/mL)

METHYLMALONIC ACID, GC/MS/MS
110 Range 87-318 (nmol/L)

[mrsD]

Did you stop your B12 supplement a few days before the test?

Or were these numbers reported before you started any supplementation?

Your B12 is high in any case...the meaning of it depends on the two questions I've asked.

[Kaybaby]

Originally Posted by mrsD

Did you stop your B12 supplement a few days before the test?

Or were these numbers reported before you started any supplementation?

Your B12 is high in any case...the meaning of it depends on the two questions I've asked.

I had not been on any B12 supplements in several weeks. My B6 was also high. I was using melatonin with B6 in it, which I have discontinued.

My B12 back in November was 907 without supplementation.

Kay

[mrsD]

Thanks for that clarification.... It could be you were really high,
and slowly came down to that figure revealed in the test.

Or it could be that you have a medical condition that creates a high B12, or you are eating fortified foods.

Some medical problems present with initially high B12.
Kidney disease
some cancers
liver problems
GI bacterial overgrowth

The transcobalamin is a bit low, and can reflect that it is being used up by the excess B12. Or that can be a genetic flaw. Transcobalamin takes the B12 that crosses the GI lining and carries it into the blood stream and around the body.

The MMA shows low and that is good because B12 is used to lower it in the body (it is a metabolic waste product).

[Kaybaby]

Thank you for the response. I had thought it was ok to supplement even though my level was 907 without supplementing. I was under the impression that higher B12 was good for neuropathy. I will not start the supps again.

Thanks again,

Kay

[Jackson Brown]

Hello, everyone.

I found this thread a few days ago and I have read the ENTIRE thing. I haven't understood some of it (haha) but I have read it and I'm so grateful for it being here. I registered specifically to share my background and ask some questions.

I am 31, male, with a history of Peripheral Neuropathy, Pernicious Anemia, lifelong vegetarianism, and a Traumatic Brain Injury (TBI).

Vitamin B12 is relevant to all of these conditions. I had my B12 checked about six months ago and it was in the low 100s. It probably has been for at least 20 years, in retrospect.

My neurologist told me start taking B12, and I did so half-heartedly because I didn't realize the importance of it. Then I got to reading and realized some of my symptoms could be related to this.

I am currently prescribed Concerta (methylphenidate) for my brain injury, and I'm wondering if this interacts in any way with B12?

The reason I ask is that prior to taking 10,000mcg methylcobalamin sublingual for a few days I used to have VERY SEVERE "drops" in energy/attention/function-ability about 3:00pm every day and I assumed it was related to "coming down from" the Concerta.

Since taking tons of B12 the past few days the drops have been noticeably less severe and smoother. I can think clearly longer into the day than I have for years (since the brain injury which left me unconscious).

After reading this thread I now wonder if my "drop" might actually be related to the levels of cortisol or B12? I'm not 100% sure how that works, so if my question sounds stupid, please just overlook me.

I'm still "fleshing out" all the information contained here, and I really REALLY appreciate it!

[mrsD]

If you were that low, then you may have a substantial anemia too. When your body replenishes B12 in the tissues, the bone marrow takes alot to make red blood cells...and these take potassium also out of the blood.

So some people become low in potassium... Eat potassium rich foods, and perhaps get tested at the doctor's..to see if you are low. Then your doctor can give you an RX for a potassium supplement. He would determine your dose based on the blood work.