[dazle]

I had a course of 3 injections of VitB from my GP and found immediately after each injection my walking was worse. One injection each week for 3. I wobbled every where but I stuck at it. My energy levels didn't increase nor my walking. Since been diagnosed with neuropathy after a neurologist tested my nerve endings. Unable to have MRI as I have a pacemaker. Have had CT scan of head, neck and spine with nothing adverse.

[Kitt]

What kind of test was done by your neurologist? And what type of neuropathy was given? Thank you.

[jcgrome]

Thank you all for posting here! Such a wealth of information & insight. I so appreciate it during this difficult period of beginning to understand what is happening to me.

[boogirl85]

mrs D, I was wondering if you could help me please.

I have been taking sublingual b12 (cyano) for about a month now, because of tingling in my arms, not being able to stand up straight, weakness and pain in the arms, back pain (I couldn't even wear a bra), and the tingling went away in 3 days, and I gradually got better, so I know my problem is a B12 deficiency (my number was 270 about 6 weeks ago) but during that time I've also had days where I would feel faint, dizzy, and my heart beating really fast - aka symptoms of hypokalemia.

I've also had 2 injections of 1ml/1mg of hydro B12 in the past few weeks, but I've since stopped taking all B12 and put a halt on the injections for now because I wasn't sure what was causing the dizziness. Before starting the B12 my arms felt weak, but at least I could think properly. But these new symptoms are scaring me.

I've had an MRI of my brain and spine and MS was discounted (no lesions), but do you think I might still have MS even if the brain scan was negative? The symptoms seem to get worse during hot whether, or after I've had a shower (I feel faint).

Why would I get these symptoms after starting B12?

Am I having a reaction to B12?

Could I have low pottasium which is causing the mental issues?

Or could my body be adjusting to suddenly having B12 after being deprived for so long?

Does taking B12 mess with blood glucose levels?

Do you think I could also have pernicious anemia (my ferritin is 10).

I also have a thread in the vitamins & supplements section if you want to read it.

Thank you so much.

[tomboy mel]

Originally Posted by MelodyL

Hi PattY;

Over two years ago, I went to iherb.com and bought the JARROWS Methyl B-12 5000. Been taking it every day since without a hitch.

Best thing I ever did for my body. I did try a cheaper one (not that this one is expensive because it's not), but I did not get the same results.

So, for me, the Jarrows is the way to go.

Best of luck

Melody

This is the kind if info I need. Thanks Mel

[nsrsg]

I have been using puritan's methylcobalamin 5000mcg every day for long time(almost an year). My condition improved a bit in the middle but now going back to the old symptoms. Recently I consulted a doctor and he prescribed two Princi-B-Forte(B1-250mg, B6-250mg and B12-1000mg) tables per day. But the B12 in the tablet is cyanocobalamin. I don't want to discontinue my methylcobalamin intake. Can I use both? will there be any side effects to that.
I could not get tablets only with B1 and B6 in it.
Thanks in advance for your suggestions.

[mrbreezeet1]

Yeah, but how do you know?
My doctor did my blood work, and says it's normal.
Says the "B" Vitamin is OK.
I don't know weather to believe them half the time or not.
I have pretty good case of PN in my feet after Chemo treatment, and it is way worse with the onset of this cold weather.
Even in the house.
I don't even want to think about trying to go back to work right now.

[mrsD]

Never accept "normal" as a result from your doctor, for B12.

Ask for the actual result...in numbers. This is because labs still report down to the 200's as "normal" and that is not adequate if you have neurological symptoms.

The early posts in this thread have a link to a medical webpage, which discusses 400pg/ml as the new acceptable low.
Some patients may also need an MMA test to firm it up as well.

[rec60661]

thank you to all once again for this very helpful information! I was diagnosed about 6 weeks ago with PN caused by taking an antacid daily for over 10 years and Metformin over the past 18 months. I have had numbness in feet for quite a while, but when I started stumbling and tripping I took notice.

None of the docs diagnosed a b12 deficiency because serum b12 is normal; however, sudden onset of trembling throughout my body, jerking and twitching muscles every time I would stop moving led me to think it may be B12.

I have had 7 k1000 mg doses of the "cyan" type of B12 and 5 1000 mg doses of the "methyl" type (we FINALLY found a local source!). I am also taking 900 mg's of Neurontin daily to control symptoms.

My question is: My muscles are extremely weak and now my doc is suspecting MS. Is profound weakness a side effect of high dose b12 therapy?

[mrsD]

When you start B12, because of being low, the B12 is prioritized by some body mechanism to be sent to critical areas..one of which is the bone marrow.

Here it gets everything going to replace the blood cells the marrow makes. Each cell gets some B12 also, along with increased use of potassium.

If you are low in potassium to start with, or marginal, you can get extreme fatigue and weak feelings. So eating high potassium foods may help this. You can get tested as well, but potassium often shows normal or high when it is not. This is due to the lab mishandling the sample ...which involves bursting the cells and dumping the potassium into the serum. If you show a real LOW that is probably accurate. But some normals and highs may be factiticious (falsely elevated).

This fatigue will go away as you use the B12 to normalize the bone marrow cell factory.

It takes time to fix low B12. The liver, will grab some of each dose for storage, and some will go into the spinal fluid and to the brain. These 3 sites have a high affinity once the B12 therapy is started. It took you months and years to get where you are now, so be patient as your body restores itself and stores some B12 for the future.

Some people find that weak muscles may also respond to some Acetyl Carnitine. This improves mitochondrial functions which we feel as "energy" and strength. Start low at 500mg a day and you may increase if you think you need to, by 500mg a week up to 2000mg a day in divided doses.