Aloha. I have been taking 5000 each morning of the Methyl B-12. To say it kicked my PN's butt is putting it mildly, but what i really noticed is that I am able to take care of my 67 year old disabled husband (who just got home from almost a month of being in hospitals and nursing homes due to getting his blood pressure under control and not fainting anymore (which we have accomplished).

I make all appointments, I get after him to do his exercises. I go up and down stairs (and I have bad knees) and my memory is sharper than when I was in my teens.

I attribute this all to Methyl B-12. Yesterday (which was his last day in the nursing rehab facility), I gathered all the residents around the computer in the Day Room and I put on videos from youtube that I knew they had never seen in their life. I had them hear Alexander Graham Bell's Voice (that's up on youtube). One of the people wanted to see the Magruder Film on JFK. I brought that up. The best was when I brought up an old I've got a secret show from the late 50's and there was a 96 year old guest whose secret was "I saw John Wilkes Booth shoot Abraham Lincoln". You should have seen the faces on those ladies. They are all in their 80's. I taught some how to use the mouse and bring up youtube. Just simple stuff.

I left them watching Liberace and Frank Sinatra videos. They were just amazed. And I can still type 146 words a minute (even with arthritis).

I am convinced that if I didn't take 5000 of Methyl B-12 I could NEVER do what I do, (especially take care of my husband who has had Peripheral Neuropathy (idiopathic) for almost 25 years.

So in my case, Methyl B-12 was a life saver with absolutely no ill effects or side effects. In all honesty, I also grow my own food in my kitchen (I'm a sprouter, look that up and you'll see what I eat). It's really cool

Take care, Melody

[QUOTE=Malia;1136946]I've really got to read more on this thread Mrs. D. I was reading one can OD on the B's and I may just be one. I take the Benfothiamine and the Jarrow B complex and then a spritz of B-12 a couple of times a day... but I must say that my PN is feeling better than in years. I really hope for some healing of the nerves in my lower legs and feet... course I don't let that stop me... I am a real work horse but am getting older and have to be more careful of my gallop. :) I was tested awhile ago...(years) May be a good time to do it again...Any personal experience of taking too much B's?
Hi Mailia
Glad to hear the B's are helping with your pain! How much Bentofamine (B1) and B12 do you take? I also have a normal-high B12 level. my last blood test (4 wks ago) was 1050. PPC said it was too high ,but I still Supplement with 1000 mcg Methylcobalamin a day. Is there any B6 in your Jarrow B Complex? As Mrs D stated , B6 is not good for everyone. I was told to stay away from the B6 because of my SFN. I still get bad pain and burning in my lower legs and feet. I take 300 Lyrica , its not working. Was thinking about increasing my B's again without the B6. What can of Neuropathy do you have and do you have a cause for your pain. Do you take any meds with your B's?
I hope you continue to "heal"..:hug:

[QUOTE=MelodyL;1137018]Aloha. I have been taking 5000 each morning of the Methyl B-12. To say it kicked my PN's butt is putting it mildly, but what i really noticed is that I am able to take care of my 67 year old disabled husband (who just got home from almost a month of being in hospitals and nursing homes due to getting his blood pressure under control and not fainting anymore (which we have accomplished).

I make all appointments, I get after him to do his exercises. I go up and down stairs (and I have bad knees) and my memory is sharper than when I was in my teens.

I attribute this all to Methyl B-12. Yesterday (which was his last day in the nursing rehab facility), I gathered all the residents around the computer in the Day Room and I put on videos from youtube that I knew they had never seen in their life. I had them hear Alexander Graham Bell's Voice (that's up on youtube). One of the people wanted to see the Magruder Film on JFK. I brought that up. The best was when I brought up an old I've got a secret show from the late 50's and there was a 96 year old guest whose secret was "I saw John Wilkes Booth shoot Abraham Lincoln". You should have seen the faces on those ladies. They are all in their 80's. I taught some how to use the mouse and bring up youtube. Just simple stuff.

I left them watching Liberace and Frank Sinatra videos. They were just amazed. And I can still type 146 words a minute (even with arthritis).

I am convinced that if I didn't take 5000 of Methyl B-12 I could NEVER do what I do, (especially take care of my husband who has had Peripheral Neuropathy (idiopathic) for almost 25 years.

So in my case, Methyl B-12 was a life saver with absolutely no ill effects or side effects. In all honesty, I also grow my own food in my kitchen (I'm a sprouter, look that up and you'll see what I eat). It's really cool

Take care, Melody

Aloha to you!
That is wonderful news Melody. Glad to hear you and your husband have greatly improved. I also suffer from I-SFN. I take 1000 mcg of Meth-B12 for over one year now. (My lab B12 is around 1050). I'm nervous to go any higher on the B12, all my Docs say my B12 is "too high". I want to try 5000 to see if it helps the pins and needles and burning pain in my legs and feet. Not sure what to do..would appreciate any thoughts. Thank you

Marie--
 

--if you're supplementing with 1000mcg per day of B12 consistently, I'm not surprised that your B12 level is at that number; that just means you're putting a good deal of B12 into your system, where hopefully it can be utilized.

Under those circumstances, I don't think that level is too high. I've had blood draws with much higher B12 levels--one time 1864, believe it or not. I have to explain to the doctors that I supplement consistently.

This is a reminder -- glenntaj is correct.

The ranges for vitamins reflect generalized "normals" who were chosen and NOT taking any supplements.

High range B12 is desirable because getting it into the central nervous system is by passive diffusion from high to low. The lower the blood level the less gets into the CNS.

Doctors are so used to ranges in blood tests indicating disease, they think high B12 is dangerous. But there is no upper limit to B12 use...so don't worry about it.

The only concern is for the rare person with polycythemia vera... this is a rare disease of the bone marrow where too many red cells are formed. This would show up in a normal CBC screening test.

[QUOTE=Marie33;1137023] You know I really got to sit down and write the amounts down cause I don't know... first I hear about the B6. I have the Methal B's but they are sublingual and they just don't desolve and made me mad. don't know if I can just take it down. I do the liquid B's spray bottle. I really want to up my B;s but had concerns... My PN came from compression... I worked banquets and wore those horrible tight shoes all over the place, including the beach and when done my feet were screaming and I would soak in ice water... do that over and over and it killed the nerves...mylin sheath. sad. I have no Rx's on board... I hit all the numbers and don't trust them cause of the side effects ...

Another question I had... what about taking B's at bedtime? I was doing it but have recently stopped. didn't want to interfere with my sleep...

Taking high dose B complex will stimulate urine production
And interfere with sleep. Also some people get energized
With B complex.. So it is best to take it inth morning.

That's what I thought... thanks for the confirm Mrs D. Aloha :)

Increasing Methyl-B12
 

[QUOTE=mrsD;1137220]This is a reminder -- glenntaj is correct.

The ranges for vitamins reflect generalized "normals" who were chosen and NOT taking any supplements.

High range B12 is desirable because getting it into the central nervous system is by passive diffusion from high to low. The lower the blood level the less gets into the CNS.

Doctors are so used to ranges in blood tests indicating disease, they think high B12 is dangerous. But there is no upper limit to B12 use...so don't worry about it.

The only concern is for the rare person with polycythemia vera... this is a rare disease of the bone marrow where too many red cells are formed. This would show up in a normal CBC screening test.

Thank you MrsD and Glenn..
I am still supplementing with B12 even though my Level is good (high)! Do you think in your educated opinion(s), it makes sense to increase my Meth-B12 to 5000 mcg? I cant help but wonder if a higher dose of B12 (like Melody) along with B1 and Folate (800mcg) could help with the pins and needles and burning in my legs and feet (?)...