[Malia]

I've really got to read more on this thread Mrs. D. I was reading one can OD on the B's and I may just be one. I take the Benfothiamine and the Jarrow B complex and then a spritz of B-12 a couple of times a day... but I must say that my PN is feeling better than in years. I really hope for some healing of the nerves in my lower legs and feet... course I don't let that stop me... I am a real work horse but am getting older and have to be more careful of my gallop. I was tested awhile ago...(years) May be a good time to do it again...Any personal experience of taking too much B's? Aloha.

[mrsD]

Taking too much B6 affects some people but that is not common.

But one B-right daily
is not that much. If you feel better, that is good..and something to keep going.

[MelodyL]

Originally Posted by Malia

I've really got to read more on this thread Mrs. D. I was reading one can OD on the B's and I may just be one. I take the Benfothiamine and the Jarrow B complex and then a spritz of B-12 a couple of times a day... but I must say that my PN is feeling better than in years. I really hope for some healing of the nerves in my lower legs and feet... course I don't let that stop me... I am a real work horse but am getting older and have to be more careful of my gallop. I was tested awhile ago...(years) May be a good time to do it again...Any personal experience of taking too much B's? Aloha.

Aloha. I have been taking 5000 each morning of the Methyl B-12. To say it kicked my PN's butt is putting it mildly, but what i really noticed is that I am able to take care of my 67 year old disabled husband (who just got home from almost a month of being in hospitals and nursing homes due to getting his blood pressure under control and not fainting anymore (which we have accomplished).

I make all appointments, I get after him to do his exercises. I go up and down stairs (and I have bad knees) and my memory is sharper than when I was in my teens.

I attribute this all to Methyl B-12. Yesterday (which was his last day in the nursing rehab facility), I gathered all the residents around the computer in the Day Room and I put on videos from youtube that I knew they had never seen in their life. I had them hear Alexander Graham Bell's Voice (that's up on youtube). One of the people wanted to see the Magruder Film on JFK. I brought that up. The best was when I brought up an old I've got a secret show from the late 50's and there was a 96 year old guest whose secret was "I saw John Wilkes Booth shoot Abraham Lincoln". You should have seen the faces on those ladies. They are all in their 80's. I taught some how to use the mouse and bring up youtube. Just simple stuff.

I left them watching Liberace and Frank Sinatra videos. They were just amazed. And I can still type 146 words a minute (even with arthritis).

I am convinced that if I didn't take 5000 of Methyl B-12 I could NEVER do what I do, (especially take care of my husband who has had Peripheral Neuropathy (idiopathic) for almost 25 years.

So in my case, Methyl B-12 was a life saver with absolutely no ill effects or side effects. In all honesty, I also grow my own food in my kitchen (I'm a sprouter, look that up and you'll see what I eat). It's really cool

Take care, Melody

[Marie33]

[QUOTE=MelodyL;1137018]Aloha. I have been taking 5000 each morning of the Methyl B-12. To say it kicked my PN's butt is putting it mildly, but what i really noticed is that I am able to take care of my 67 year old disabled husband (who just got home from almost a month of being in hospitals and nursing homes due to getting his blood pressure under control and not fainting anymore (which we have accomplished).

I make all appointments, I get after him to do his exercises. I go up and down stairs (and I have bad knees) and my memory is sharper than when I was in my teens.

I attribute this all to Methyl B-12. Yesterday (which was his last day in the nursing rehab facility), I gathered all the residents around the computer in the Day Room and I put on videos from youtube that I knew they had never seen in their life. I had them hear Alexander Graham Bell's Voice (that's up on youtube). One of the people wanted to see the Magruder Film on JFK. I brought that up. The best was when I brought up an old I've got a secret show from the late 50's and there was a 96 year old guest whose secret was "I saw John Wilkes Booth shoot Abraham Lincoln". You should have seen the faces on those ladies. They are all in their 80's. I taught some how to use the mouse and bring up youtube. Just simple stuff.

I left them watching Liberace and Frank Sinatra videos. They were just amazed. And I can still type 146 words a minute (even with arthritis).

I am convinced that if I didn't take 5000 of Methyl B-12 I could NEVER do what I do, (especially take care of my husband who has had Peripheral Neuropathy (idiopathic) for almost 25 years.

So in my case, Methyl B-12 was a life saver with absolutely no ill effects or side effects. In all honesty, I also grow my own food in my kitchen (I'm a sprouter, look that up and you'll see what I eat). It's really cool

Take care, Melody

Aloha to you!
That is wonderful news Melody. Glad to hear you and your husband have greatly improved. I also suffer from I-SFN. I take 1000 mcg of Meth-B12 for over one year now. (My lab B12 is around 1050). I'm nervous to go any higher on the B12, all my Docs say my B12 is "too high". I want to try 5000 to see if it helps the pins and needles and burning pain in my legs and feet. Not sure what to do..would appreciate any thoughts. Thank you

[glenntaj]

--if you're supplementing with 1000mcg per day of B12 consistently, I'm not surprised that your B12 level is at that number; that just means you're putting a good deal of B12 into your system, where hopefully it can be utilized.

Under those circumstances, I don't think that level is too high. I've had blood draws with much higher B12 levels--one time 1864, believe it or not. I have to explain to the doctors that I supplement consistently.

[mrsD]

This is a reminder -- glenntaj is correct.

The ranges for vitamins reflect generalized "normals" who were chosen and NOT taking any supplements.

High range B12 is desirable because getting it into the central nervous system is by passive diffusion from high to low. The lower the blood level the less gets into the CNS.

Doctors are so used to ranges in blood tests indicating disease, they think high B12 is dangerous. But there is no upper limit to B12 use...so don't worry about it.

The only concern is for the rare person with polycythemia vera... this is a rare disease of the bone marrow where too many red cells are formed. This would show up in a normal CBC screening test.

[Marie33]

[QUOTE=mrsD;1137220]This is a reminder -- glenntaj is correct.

The ranges for vitamins reflect generalized "normals" who were chosen and NOT taking any supplements.

High range B12 is desirable because getting it into the central nervous system is by passive diffusion from high to low. The lower the blood level the less gets into the CNS.

Doctors are so used to ranges in blood tests indicating disease, they think high B12 is dangerous. But there is no upper limit to B12 use...so don't worry about it.

The only concern is for the rare person with polycythemia vera... this is a rare disease of the bone marrow where too many red cells are formed. This would show up in a normal CBC screening test.

Thank you MrsD and Glenn..
I am still supplementing with B12 even though my Level is good (high)! Do you think in your educated opinion(s), it makes sense to increase my Meth-B12 to 5000 mcg? I cant help but wonder if a higher dose of B12 (like Melody) along with B1 and Folate (800mcg) could help with the pins and needles and burning in my legs and feet (?)...

[mrsD]

B1 can be helpful. In the old days, Thiamine was a treatment given by doctors for people with neuropathy. I think it is worth a try. If you take folate, do the methylfolate type, just in case you have that MTHFR genetic mutation that control methylation.

If you have a level of B12 using methyl form at 1000 or more you don't need to increase your B12. 1mg a day should be enough.
But if you tested and did not stop taking it before the test, your levels may be artificially elevated, and inaccurate.

[Malia]

That good to know.... and I do know that it has improved my PN. I just bought some gummies to pop during the day too... so a spritz here and a pop there plus my Jarrow B's/Benfo with my morning smoothie... I am a happy girl Thanks...

[MelodyL]

[QUOTE=Marie33;1137568]

Originally Posted by mrsD

This is a reminder -- glenntaj is correct.

The ranges for vitamins reflect generalized "normals" who were chosen and NOT taking any supplements.

High range B12 is desirable because getting it into the central nervous system is by passive diffusion from high to low. The lower the blood level the less gets into the CNS.

Doctors are so used to ranges in blood tests indicating disease, they think high B12 is dangerous. But there is no upper limit to B12 use...so don't worry about it.

The only concern is for the rare person with polycythemia vera... this is a rare disease of the bone marrow where too many red cells are formed. This would show up in a normal CBC screening test.

Thank you MrsD and Glenn..
I am still supplementing with B12 even though my Level is good (high)! Do you think in your educated opinion(s), it makes sense to increase my Meth-B12 to 5000 mcg? I cant help but wonder if a higher dose of B12 (like Melody) along with B1 and Folate (800mcg) could help with the pins and needles and burning in my legs and feet (?)...

Hi there. I now have Alan taking the same Methyl B-12 that I do. He needs to ramp up his energy. This will take time but I don't see any ill effects.

I have had doctors pooh pooh my taking Methyl B-12 and then ask me quietly later 'Melody, I have neuropathy, can you tell me about that B-12 again". These are DOCTORS who are supposed to KNOW. Yeah, they know Pills and Drugs, not what supplements can help people with PN.

It amazes me sometimes.

Why not try the 5000 for awhile?. I knew right away that this is the amount that would help me.

And get ready if you share this with your doctor. He'll say you are crazy and what the h are you doing? Thank god, my primary care guy is a bodybuilding physician who knows all about my Methyl B-12 and my sprouts. I just brought him a ziplock bag of my sprouts into his office during Alan's appointment on Friday. He took one look and said "Oh my sister will put this in my salad tonight. I love these things".

So some doctors know good stuff and some doctors don't know a darn thing about anything.

We have had specialists come to our neuropathy meetings just to learn from US.

And while Alan was in the hospital (you are going to LOVE this) a doctor waltzed in, told Alan he was a neuropathy specialist and told Alan 'you have diabetic neuropathy". Alan said "Sir, with all due respect I have had neuropathy for over 20 years and I'm a diabetic only 3 years" I was tested all those years with glucose tolerance tests and every test known to man, I did NOT get PN because I was diabetic"

What was the doctor's response to Alan: "you don't know what you are talking about, OF COURSE YOU WERE DIABETIC"

See what I mean?

Some of them are clueless and don't know what they are talking about.

Melody