[mrsD]

2500mcg = 2.5 milligrams

This is not completely absorbed, orally.

And yes, there is no upper limit set for B12 by the FDA.

If you take it for 3 months and see no improvement at all,
you can assume you don't need it. You can then take it
once or twice a week, to maintain.
You should really get the numbers from your test for a definite
answer.

Not all PNers have low B12 (below 400 US units).

Originally Posted by Idiopathic PN

Mrs. D, I am taking now Vit.B12 (methycobalamin) 2500mcg. I am not sure if this should be the right dosage for me. I have bad burning, prickling, stabbing "pins and needles" in both my legs and arms. Sometimes, the sensations in my arms are tolerable but the sensations in my legs remain consistent. The touch of my clothes, even h ow soft, causes so much pain in my skin. My feet, are always painful making it difficult to walk and stand.

My symptoms are not typical as describe by some that it starts in the feet and progresses upward. Mine was simultaneous in my feet, legs and arms.

When I was tested for Vit B12 and Folate Serum (due to another condition) last May 2011, the results were within very comfortable normal range. Since the onset of my neuropathy symtoms last October 2011, I was never tested again. My 2 neurologists just sort of used that May 2011 as the basis.

Did I get you right that there is no overdose of VB12? What is the difference between mcg and mg?

Thank you.