thanks mrsD. What supplement would help me sleep at night my mind keeps racing. As far as magnesium I have Magnesium Glycinate will this work.

Yes, glycinate works.

The magnesium should help. Do your epsom soaks before bedtime and it will help.

Thanks.
Question. I was taking acetyl-L-carnitine 500 mg;/day and a-lipoic acid 600 mg /day..I remember reading that this can work like a stimulant, It did in me could not focus felt hyped up could not sleep. I stopped taking and now I feel fine, I would like to take these but not sure if I would get the benefit if I take one every 3 days so they are not taken together or would it be better to take in a 50 mg/day to start and see how they work.

Thanks

sorry I am late to answer you. I typed out one yesterday and hit send and left this laptop which went into some cyber ether problem. I seem to have wifi with ATT go wonkey here in my living room.

I guess that post got lost then, as I discovered last night that my answer never posted.

Some days things seem okay and others, well, I get error messages!

Let me try again...

Both of those supplements you mention are specific for mitochondrial energy production. I typically only suggest them after the more common supplements fail.

I tend to think that if someone gets revved up from something it might indicate you are not low with them. Or that you are taking too much.

You could try a low dose every other day, and see if you see any changes in your PN. It is best to go slowly than taking many new things all at once. Try to resist the common, pill popping that people in the US tend to do. It may be that one common supplement will be your best bet, but taking too many things at once in the beginning, may hide that information from you.

Be aware, that lipoic acid is available in 3 different forms and the dosing for each is quite different.

I think I accidentally discovered that R-Lipoid-Acid is critical to my comfort. At some point over past few weeks, I finished a bottle of it, and forgot to open a new one. It fell out of my supplement regimen.

In mid-January I started what I thought was a typical 2 or 3 day flare, but instead, it just kept getting worse and worse and over the next 3 weeks. By last Friday night, my feet were on fire and I was feeling near constant "rushes" body-wide. I hadn't felt that bad since 2014, and I was worried I was progressing and getting pretty scared.

When I was getting my supplements all divvied up for the week on Saturday, I suddenly realized that I didn't have RLA in the mix. I couldn't remember when I'd run out, but it had to have been a few weeks. I had a new bottle ready to go, but just hadn't opened it.

Long story short, as soon as I started back up with it Saturday morning, I started seeing improvement, and today I'm just about back to normal (my normal...not normal normal).

I'm going to assume it's not just a coincidence.

I have this reaction when I try to eliminate SAMe. I had stopped
it for the 4th time, and bingo my left (good knee) went out! Still have to wear a light brace though.

So I am back on 400mg a day and slowly improving! sigh.

My joy was short-lived, as was the flare-relief. I've returned to full flare status.

Update.
I am taking the supplements and concentrate on the B12 in the morning before I get up at east 2-3 hours so it is on a empty stomach. Only been doing this for close to 2 months. I don’t have the burning on the top of my feet and up my shins any more. I soak my feet a couple time a week and it really helps.
I can really tell that I was lacking in a lot of nutrients, my legs don’t cramp any more, climb stairs my legs don’t feel heavy and tired.

I have some days where things feel somewhat normal, whatever normal is.

In a way things feel like they are stable and getting better. I really feel this was caused by using PPI for 7-8 years and not taking supplements and all of this started in my right foot 4 years ago and my neurologist was clue less he thought it was from my spinal stenosis in L4-L5.

I do think it is a contributing factor to this because if I roll over on my back in the middle of the night my legs go numb from my hips to my feet…than when I move to one side I can feel the feeling come back when I told him this it did not seem to matter to him. I have changed Dr’s and go to the new Dr 3/13 to discuss this.

Thanks for all the help on this

mrsD when i had my tests it came back that my Folate was greater than 24ng/ml I feel that my condition was caused by B12 deficiency from use of PPI for 8 years. I am taking 5000mcg B12 every morning is there any thing else I should be doing or increase this for a few months.

Thanks for the help