My husband fortunately was able to give me the injections at home. I started B12 injections as well as oral supplements on April 7. I also started acupuncture the same week. The burning in my legs was horrific. I screamed all night and cried all day. I had pain in my thighs as well. I could not sleep and was prescribed Ambien. I was able to sleep with the Ambien but also got very depressed while on the Ambien and quit eating, thus losing over 10 lbs in short order. I was then prescribed Paxil. I was spiraling down very fast and not wanting to live if I had to have this pain all my life and take all kinds of drugs to control the pain. However, by week five on the injections, supplements, and acupuncture my body finally began to rally. The burning and pain in my legs stopped and now the numbness in my feet and hands is almost completely gone. I was fortunate to have a wonderful support group of family and friends who prayed for me daily and I know that God has answered all our prayers.

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I have chemo induced PN and take 5K mcg of B12 daily. I had started out having B12 injections on a weeky basis but switched to the oral form. I would like to know how often you do the injections and what the dosage is as I considering resuming injections.

I would also like to know which supplements you use besides B12. TIA

Mrs. D

What form of curcumin do you recommend. I recall on another post you saying there was a certain form you would recommend, but don't recall you posting the details. Thanks in advance

There are several enhanced forms of curcumin out there now.

Curcugel is affordable and I have used it.
There are also forms with Bioperine added, but if you take RX drugs I'd prefer you avoid Bioperine products until more research clears it as safe. Bioperine enhances absorption of many things, and drugs were not developed in dosing relating to it.

This is a long thread, but it has alot of information on it that is useful to help you select a product you can afford, and that will work:

http://neurotalk.psychcentral.com/sh...light=curcumin

The Parkinson's forum also has many curcumin threads, as they use it too. Some of theirs is more research oriented, but if you search there you will find plenty to read also.

Regular curcumin that is not enhanced, will remain in the GI tract and act as an antioxidant there. Good for Crohn's, and other inflammatory problems localized to the GI tract.

Mrs D,
Do you know anything about the potential effects of resveratrol on PN?

I can only assume it would be helpful. That is if you get good quality resveratrol.

I think antioxidants are useful for PN...they quench free radicals etc. I take 300mg grapeseed extract daily, and krill oil has one in it too...to make it the red color.

And there are the studies showing simple Vit C in high amounts of 500 to 1000mg can prevent onset of RSD from surgery on the foot or hand. That is something to think about. RSD being a neuropathy of the sympathetic nerves. Why is not understood, but inflammation must be at the heart of that action.

So if you can afford resveratrol, I say give it a try.

Thank you MrsD.
I notice you have recommended Puritan's Pride as a source of supplements in many of your responses - does it have better prices than other providers?

Puritan's has better prices on some things, but not others.

For example with the sale going on now, for d-ribose (which is expensive), buy one get 2 free... I saved about $30. (over iherb)

They do raise their prices for "sales", but even then they can be a "deal". I used to get my grapeseed extract from them, but then Costco started carrying a nice softgel type, so I bought that last time.

After you buy from them once, if you give your email, they will send occasional emails, for free shipping + perhaps a $$ discount coupon. The buy one get 2 free is the major sale I use.
I don't think the savings on their other sales is as great. They only do this one once a year in summer typically. (If you save your catalogs from them, you will see they alter prices according to sales-- this bothers me somewhat, but I think you still save alot in the end.)

In the past Puritan's did not have the "newest" supplements, but I see that is changing. They now have methylcobalamin and the d-ribose which I had purchased at iherb previously.

I think their quality is fine. I've used them for years. But just not for everything.

I am a new user with perpherial neuropathy but I cannot figure out how to post a question to the site.
Debbie

You're doing just fine caldeb1, but you're in the 'tips' section at the moment!

Under here I've provided a link. If you click that link it'll take you to the main PN forum, and you can either reply to a thread already commenced, or start one of your own.

http://neurotalk.psychcentral.com/forum20.html

Towards the top, on the left you'll see new thread or post reply, depending on what page you brought up.
Click on that one and you're away!

Good luck, and let us know if you need any more assistance.

Mrs. D - Thank you for sending me the link to all the posts about supplements for PN and the links to articles about PN (causes, diagnosis, and treatments). All very helpful!!!

I know all supplements/treatments won't work for all types of PN. What do you know about PN caused by autoimmune disorder, like Sjogren's Syndrome, or caused by autonomic nervous system dysfunction. If PN has one of those causes, will supplementation still be effective? Or is PN that is caused by autoimmune or autonomic problems less responsive to supplementation therapy? I can't remember where I got this sense, but I remember seeing this somewhere. Hopefully I am wrong.

Thank you.