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Old 02-03-2012, 01:00 PM #1
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Most vitamins can be taken with food.

Exceptions.

1) Separate B12 oral should be on an empty stomach.

2) Lipoic acid is absorbed better on an empty stomach.

3) acetyl carnitine is best broken up into several doses and not taken all at once in one large dose.

4) Products in oils, are best taken with food.

5) calcium supplements are best taken in divided doses too.

I think you should get tested for Vit D and B12 to see where you are presently. This would then point to how much you need if you really need them. Zinc can be tested for too.
Zinc is unlikely to be low unless you take ACE inhibitors for blood pressure, or daily acid blocking drugs. Prednisone and birth control pills may lower zinc levels too. People eating meat, and seafood, do not get low in zinc as a rule.

Choice of which supplements to start on and concentrate on depend on your medical history. What is causing your PN?
Trauma/injury? at a young age? Type I diabetes? Hereditary? Supplements may not work on hereditary patients. Heavy use of therapeutic agents that damage nerves...chemo and other drugs? Lupus?

If you have a basic nutrient deficient PN from low B12, the other supplements are less important, than fixing the B12 first.
If you add too many together in the beginning you cannot see which of them are working and which are not.
Since magnesium is needed and commonly low, taking a good
product (not OXIDE type), at 1/2 the RDA is helpful. Many people in US are low in magnesium...not just diabetics and PNers.

The B-complex, C, and magnesium are useful for many people other than PNers. It all depends on what your diet is like, and your medical history, and drugs being taken, OTC and RX.
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Old 02-03-2012, 05:10 PM #2
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Question Thanks!!!

Quote:
Originally Posted by mrsD View Post
Most vitamins can be taken with food.

Exceptions.

1) Separate B12 oral should be on an empty stomach.

2) Lipoic acid is absorbed better on an empty stomach.

3) acetyl carnitine is best broken up into several doses and not taken all at once in one large dose.

4) Products in oils, are best taken with goof.

5) calcium supplements are best taken in divided doses too.

I think you should get tested for Vit D and B12 to see where you are presently. This would then point to how much you need if you really need them. Zinc can be tested for too.
Zinc is unlikely to be low unless you take ACE inhibitors for blood pressure, or daily acid blocking drugs. Prednisone and birth control pills may lower zinc levels too. People eating meat, and seafood, do not get low in zinc as a rule.

Choice of which supplements to start on and concentrate on depend on your medical history. What is causing your PN?
Trauma/injury? at a young age? Type I diabetes? Hereditary? Supplements may not work on hereditary patients. Heavy use of therapeutic agents that damage nerves...chemo and other drugs? Lupus?

If you have a basic nutrient deficient PN from low B12, the other supplements are less important, than fixing the B12 first.
If you add too many together in the beginning you cannot see which of them are working and which are not.
Since magnesium is needed and commonly low, taking a good
product (not OXIDE type), at 1/2 the RDA is helpful. Many people in US are low in magnesium...not just diabetics and PNers.

The B-complex, C, and magnesium are useful for many people other than PNers. It all depends on what your diet is like, and your medical history, and drugs being taken, OTC and RX.
I was confused wether this answer was for me? If so I will try to get tested I began my neuropathy years ago but the tingling just started I don't take any meds either... How much lipoic acid and acetyl carnite should I takedaily?
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Old 02-03-2012, 05:21 PM #3
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This answer is generic...for everyone.

If you choose the R-lipoic stabilized, 100mg a day to start is
a good dose. You can raise it later if you tolerate it. Some of us
find it too stimulating in higher doses. This new form is so much more absorbed than the older forms, 100mg is a good dose for most people.

The acetyl carnitine would be 500mg a day to start, and work up to 2 grams a day divided doses, if necessary.

These are for mostly mitochondrial damage. If your PN is not of this type, they may not work. The lipoic acid will also improve glucose utilization, and provide some antioxidant effects. It is more globally acting than the carnitine. The acetyl carnitine has been used for chemo drug damage and HIV drug damage.
Both cause toxic neuropathies.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

************************************

.
Weezie looking at petunias 8.25.2017


****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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