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-   -   ~MEDICATIONS~~ That May Cause Peripheral Neuropathy (https://www.neurotalk.org/pn-tips-resources-supplements-and-other-treatments/122889-medications-cause-peripheral-neuropathy.html)

richmirth 10-11-2010 08:56 PM

Seroquel
 
I believe that Seroquel definitely caused my peripheral neuropathy (PN). Will stopping the drug, as I have one month ago, allow me a remission? I had taken the Seroquel for about 5 years.

Will valium relieve symtoms of PN? It seems my walking is worse with taking of valium.

mrsD 10-12-2010 09:44 AM

Welcome to our board!

Quote:

Originally Posted by richmirth (Post 703627)
I believe that Seroquel definitely caused my peripheral neuropathy (PN). Will stopping the drug, as I have one month ago, allow me a remission? I had taken the Seroquel for about 5 years.

Will valium relieve symptoms of PN? It seems my walking is worse with taking of valium.

I could not find a specific thing on PubMed for this drug and neuropathy. However, this drug and others in its class can greatly impact metabolism and sugar control, and these things then can create a neuropathy. It would be similar to diabetic neuropathy or insulin resistance. Also this drug raises triglycerides, and that makes the blood thicker, and thicker blood can cause neuropathy sensations in the hands and feet.

Drugs like Xanax, Valium, and Klonopin are useful in the short term for reducing sensory burning, and other feelings in the skin. But over long term use, they induce an habituation, which then leads to MORE burning sensations, and when trying to discontinue them, can be very painful and difficult.

You might want to look at my supplements thread here, because some diabetic neuropathies respond to:

alpha lipoic acid (or the newer r-lipoic)
acetyl carnitine
benfotiamine ( a better form of thiamine B1)

You really should look at B12 and Vit D. (some type II diabetics have low D levels). Your B12 should be above 400, and your D should be above 50ng/ml. (some doctors think lower levels are "normal" and that is out of date information).
Brings these two up to normal can also help.

Tulips 10-15-2010 11:40 AM

I took levaquinn 2002 for three days and stopped cause I had rash. But again I already had my symptoms way before this. But either along the way these things worsened my situation or added a problem.

I have taken
Augmentin, biaxin, zpack, clindamycin, bactrim
Omnicef.
So I guess it's impossible at this point to say what did this and again if it's medicine or a disease.

mrsD 12-24-2010 06:23 AM

Tindamax:
 
http://www.rxlist.com/tindamax-drug.htm

This drug is new, and chemically related to Flagyl (metronidazole).

Quote:

Neurological Adverse Reactions

Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, have been reported in patients treated with tinidazole. The appearance of abnormal neurologic signs demands the prompt discontinuation of tinidazole therapy.
It is currently approved for:
Trichomoniasis
Giardiasis
Bacterial Vaginosis
Amebiasis

Flagyl is a known causer of PN also.

kate525 01-26-2011 09:42 AM

I have been on many antibiotics over the years and have seen several infectious disease docs who have all agreed that Flagyl and Tindamx can cause neuropathy. If you research the respective PI, you will see neuropathy listed as a potential side effect.

mrsD 03-20-2011 01:52 AM

Here is a link to a paper from 1979 which while old and will not have newer drugs on it, still lists the drugs that may cause neuropathies. They are listed according to type of PN which may be helpful for some people visiting here.

http://docs.google.com/viewer?a=v&q=...Jqu4UctUx33kIA

mrsD 10-21-2011 07:10 AM

links broken in first post....
 
I checked this thread today, and found some links have expired, or the site was changed.

I am going to try and find a better resource, but this topic is difficult to find on the net.

I'll keep looking so we can have a useful list here. (I should have copied them....dang...but we have copyright rules here which prevented me from doing so.).

This is another list, also incomplete:
http://www.neuropathy.org/site/News2...s_iv_ctrl=1221

This link has a list of the various heavy metal poisons and solvents that can cause neuropathy:
http://emedicine.medscape.com/article/1175276-overview

This one is also incomplete, but has some agents listed missed by the other lists: Merck Manual:
http://www.merckmanuals.com/professi...europathy.html

Sallysblooms 01-26-2012 04:55 PM

I will make a list, hard to pick out the meds. Is there a list?

Also, I wonder if there is a "safer" antibiotics. The only one I can take safely is Duricef. Old one but I have never had a problem. The others have given me side effects. They are life saving, but they sure are serious meds.

mrsD 01-26-2012 05:26 PM

Technically only certain antibiotics make the "list"....

Flagyl, fluoroquinolones, and others mentioned here.

BUT...some autism sites mention other antibiotics used long term may damage mitochondria also... I recall amoxicillin mentioned.
This is because some kids with autism diagnoses, have had long term "simple" antibiotics for chronic ear infections, and they were looking at that as a possible mito disruptor. Those antibiotics have not made it the lists as the clinically reported ones because the reported ones made it on short term usage. Mitochondria are decendents of bacteria and as such would be prone to damage from drugs that kill bacteria.

Click on the links on all the posts here to see the lists.
The longest list was at Wrong diagnosis website, which was totally changed and overhauled and that is no longer on the web, for whatever reason now.

Sallysblooms 01-26-2012 07:25 PM

Yes, long term use is always a different story.:( I do know Gentamicin is Ototoxic, BAD news. My ENT told me never to take that and I stay away from all micins.

Are floroquinalones on this list? Same as quinalones I guess, I had to take Cipro when my Duricef didn't work for the last UTI. OUCH, I had muscle pain.

Leviquin is a foroquialone, yikes. I had to take it once for a bad Diverticulitus attack. They are all so scary. Would be nice if I could find another one I can take in case I need it. Thank goodness for Duricef.

http://www.emedexpert.com/lists/antibiotics.shtml#5


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