Whilst researching pregnenolone, I came across a graphic that included pantothenic acid (vitamin B-5), calling it the "stress vitamin", and saying that it "drives the process" of converting pregnenolone into other hormones. Curious about this, I Wiki'd pantothenic acid, and found this statement:

This was all new to me (What isn't? ) In everything I've read here (NT) and elsewhere, I don't recall seeing this mention of B-5 in conjunction with alpha-lipoic acid with regard to PN (not that I couldn't have missed it, though I just searched and still didn't see anything).

So I checked my daily B-100 complex (which I take mornings along with my R-Lipoic acid anyway) and find it contains 100 mg. of pantothenic acid (hope that's enough - it's 1000% of the RDA... yeah, yeah, I know )

Anyhoo, since I don't recall seeing it anywhere before, I thought I'd mention it for consideration/dissection/demolition.

FWIW,

Doc

Vitamin B5 is rarely deficient in most people. There are claims for it, but not commonly, to use extra.

A version called panthethine has been linked to lowering cholesterol but never panned out in a big way.

I think your B complex is enough, unless you want to try more.

I might if the burning pain ever comes back and/or I need to increase the R-Lipoic (currently 100 mg./day). After finding the initial reference, I got to thinking it could explain my atypical (beneficent) results, as I take them together in the morning.

Doc

I have PN as an outgrowth of Waldenstroms cancer. My neurologist recommended a salve that is formulated by a local pharmacy.
The contents are:

Flurbipropen 10%
Amitriptyline 2%
Gabapentin 6%
Lidocaine 2%
Prilocaine 2%

Lipoderm(R) Activemax

If anyone would like to try something like this, and can't get formulated at their local pharmacy, write me at gyrene070@yahoo.com and I'll put you in contact with my pharmacy.

Tom