@ElaineD:

Here are some medical papers discussing the safety of using proton pump inhibitors with NSAIDs:

http://agajournals.wordpress.com/201...e-from-nsaids/
When this inflammation occurs all sorts of nutrients and minerals will suffer because they can no longer be absorbed by the damaged intestine.

This link is a long paper on Stomach ulcer prevention only:
http://arthritis-research.com/content/15/S3/S5

This article brings up the topic of bone loss doing this treatment.
http://www.wisegeek.com/what-are-the...id-and-ppi.htm
This is because acid in the stomach is necessary for proper Vit D absorption of calcium (and also magnesium). I mentioned this nutrient interaction in just above this post.

There is always a price to pay for using complex drugs for long periods of time (as in arthritis therapy). You'll have to decide how much risk you are willing to take, and remain vigilant for any signs of intestinal warning symptoms.