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Old 10-04-2015, 07:34 PM #1
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Default Some hope on the horizon

Has anyone heard of the clinical trials that are to start in Switzerland for Atexakin Slfa as the first disease modifying drug for neuropathic? Hoping to reduce pain, improve nerve conductivity and nerve regeneration. Does sound a little too good to be true - but we can hope.
Relief Theraputics are the company licences to start clinical trials
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Old 10-05-2015, 09:06 AM #2
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Cool Smirk

Here is a Link to a short article:

http://www.pharmaceutical-technology...atment-4665940

Dave.
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Old 10-05-2015, 11:24 AM #3
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Originally Posted by EnglishDave View Post
Here is a Link to a short article:

http://www.pharmaceutical-technology...atment-4665940

Dave.

Sounds promising.


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Old 10-05-2015, 11:47 AM #4
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Wink

Looks good to me, and it already has passed other studies which means it may not be long coming to us finally.
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Old 10-05-2015, 12:10 PM #5
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looks good to me, and it already has passed other studies which means it may not be long coming to us finally.
line forms behind me! That said, it looks like this may not be helpful to small fiber neuropathy sufferers or those with axon damage. Unless I am reading it wrong?
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Old 11-29-2015, 07:58 PM #6
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line forms behind me! That said, it looks like this may not be helpful to small fiber neuropathy sufferers or those with axon damage. Unless I am reading it wrong?
Diabetic neuropathy is a form of small-fiber nerve damage, and they're also somewhat general in their statement ("associated with neuropathies") so I'm thinking this will have general use. Adding bold & italic to the bits I think are especially cool --

Quote:
The company noted that atexakin alfa has the potential of relieving pain, as well as non-pain symptoms associated with neuropathies by restoring normal innervation in the periphery.
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Old 11-30-2015, 01:24 PM #7
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Looks good to me, and it already has passed other studies which means it may not be long coming to us finally.
and I'm sure the insurance companies will eagerly completely cover these no problem <sarc>
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Old 11-30-2015, 08:54 PM #8
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http://neurotalk.psychcentral.com/thread228927.html
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Old 11-30-2015, 10:35 PM #9
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After reading the press release a bit closer, it appears that they have yet to even start Phase II trials - "Relief will engage in clinical development to evaluate the therapeutic efficacy of atexakin alfa...."

In Phase II and III, it is not uncommon to have 6 month delay to even get the trial started. The average Phase III trial lasts over 2 years, give or take - depending on the indication. And that is just the trial time. That doesn't include all the stats, analysis, write up, review, and FDA filing etc.

I'm probably less interested in this knowing that it is a Disease Modifying Drug and will probably have a significant side effect profile. However, I will keep one eye on this one....
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Old 08-09-2016, 05:39 AM #10
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Book Atexakin studies

Does anyone know at this time the status of the studies of Atexakin.
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