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-   -   Histamine reactions and PN: (https://www.neurotalk.org/pn-tips-resources-supplements-and-other-treatments/161714-histamine-reactions-pn.html)

janieg 09-26-2021 08:52 PM

Sorry for the delay in getting back to you.

So glad you were eligible for that new treatment!!! Disease-free is amazing. Very happy for you.

That was definitely an interesting conversation you had with the pharmacist. Which antihistamine are you going to take? I'm taking Zyrtec daily now, but all it does is keep the histamine away from my H1 receptors. Since my CNS is getting hit, I think that means my H3 receptors are the ones absorbing it all.

Lara 09-27-2021 03:33 PM

Thankyou!
Well, I would usually just have Claritin (loratadine) nearby because I have had a Tick Anaphylaxis and always need to be prepared. I was told a few weeks ago, when talking about the vaccine reaction, to change this to Telfast 180mg (fexofenadine) which I think may be called Allegra in the US. It's supposed to work faster as well.

I read so much about all the different newer generation antihistamines that it boggled my mind and never did figure out which one would be the best. These are the non-sedating ones mind you. After reading your message I looked into H3 receptors and came across something called Pitolisant that's used to treat narcolepsy. You would understand all the technical papers better than me. I just kept getting confused.

from British Journal of Pharmacology Feb 2020
Histamine, histamine receptors, and neuropathic pain relief

take care there


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