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05-26-2012, 07:43 AM | #1 | |||
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Wisest Elder Ever
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I am only saying that the nortriptyline may be more effective than the gabapentin. (new meta analysis of gabapentin found it only effective in about 30% of cases).
For that reason it is worth trying it. If it works well, you could consider tapering off gabapentin to see which is doing more for you. People all vary in responses to drugs, so one has to try them to see. More on nortriptyline: http://en.wikipedia.org/wiki/Nortriptyline Usually low doses of this drug work for PN.
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05-26-2012, 11:24 AM | #2 | ||
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Quote:
As you know, I am open to every medication available in the market, just to help me with the pain. I just have to get more information from experts like you - and for people who have actually used it. Thanks for your time. |
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05-26-2012, 11:26 AM | #3 | |||
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Wisest Elder Ever
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When you first start, there may be some sedation. That usually wears off in a week or so. The doctors give it at night for that reason.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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"Thanks for this!" says: | Idiopathic PN (05-26-2012) |
05-26-2012, 09:54 PM | #4 | ||
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Mrs.D, in your experience, how long does a particular medicine reach its maximum effectiveness? I have read in some posts here that after reaching a maximum dosage for gabapentin, it stops working - and that applies to Nortriptyline too. My word...... how will manage our pain???? |
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05-27-2012, 12:13 AM | #5 | |||
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Wisest Elder Ever
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I think insomnia is less likely than the reverse.
In antidepressant doses, the side effect profile is typically different than in the lower doses used for PN. It can take up to a month to see effects. When I tried amitriptyline (the parent compound) last winter I had pain relief within 3 days. But that wore off in the low dose I was taking after about 10 days. Because it made my blood sugar go up, I discontinued it. No sense in raising the dose etc, for me. Nortriptyline is the active metabolite of amitriptyline (Elavil). So their actions are very similar.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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05-27-2012, 07:26 PM | #6 | ||
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Dear Mrs.D,
I was given 10mg 1x a day to be increased to 2x a day on the second week. I understand that lower dosage of this medicine is intended for pain, but can it also improve the mood without increasing the dosage? I am not sure Mrs. D but, I think my mood needs improvement. That is why I keep on taking SAM-e because aside from my arthritis which is really bothering me, I was hoping it can help my mood. but i notice that with the current dosage I am taking (200mg), I dont feel any change in my and instead I feel anxious. My plan was to increase the dosage so my arthritis can benefit more but with the nortriptyline coming in the picture, this will of course change. By the way, thank you very much for advising me to stop SAM-e should I decide to take Nortriptyline. That was very thoughtful of you to advise me of the contraindication between the two. If I stop SAM-e, is there anything that you can recommend for my arthritis? Mrs.D, as I mentioned in my earlier post, constipation is a problem to me now, Nilram warned me that constipation is one of hte side-effects of Nortriptyline, is taking virgin olive oil on daily basis safer than taking Metamucil, meaning that would it not affect the absorptions of all the drugs and supplements I am taking? As you know, with all my prescribed medicines and supplements, I have very little window for Metamucil. Lastly (for now...), I understand that calcium affects the absorption of some prescribed medications, does it also affect the absorption of the supplements/vitamins? Thank you so much. Quote:
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05-28-2012, 04:51 AM | #7 | |||
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Wisest Elder Ever
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Have you tried topical things for your finger swelling?
Salonpas patches OTC may help. The original ones can be cut to size to fit over fingers. Have you soaked that hand in epsom salts? If the SAMe is making you anxious, you may not need it. Side effects are more common in people who already have enough SAM being made in their bodies. I am also wondering about that finger... Is this what you have? http://www.orthogate.org/patient-edu...ntracture.html Have you seen a hand specialist at all?
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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