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-   PN Tips, Resources, Supplements & Other Treatments (https://www.neurotalk.org/pn-tips-resources-supplements-and-other-treatments/)
-   -   New research into Neuropathic pain: (https://www.neurotalk.org/pn-tips-resources-supplements-and-other-treatments/222678-research-neuropathic-pain.html)

mrsD 07-20-2015 05:07 PM

Deja.... do you know about the magnesium lotion? Magnesium also blocks the NMDA receptors in the periphery.

Morton Epsom lotion:
Many of us here use it with great success. It also relaxes muscles and improves circulation.

This is inexpensive and works wonderfully, it even lowers my hypertension to almost normal. I only need a small dose of betablocker now instead of 3 drugs.

Walmart and Walgreen's have it on the shelf...and it is at Amazon online... but not all stores have it yet.
Use about a quarter's diameter once a day...at night if possible.
Divide that up 1/2 for each leg. I find it lasts more than a day for me, so you can rotate locations. A fingertip dollop works for the neck.

http://www.walmart.com/ip/Morton-Uns...fl-oz/23711655

DejaVu 07-20-2015 05:20 PM

Hi MrsD,

Thanks for mentioning this to me! :)
I had found this lotion just 2 months ago, by chance, at Walmart.
I use it nightly.
Thanks for the dosage info. I will use it more frequently, and in more areas!

It's good to be back here on the PN forum, and at neurotalk in general!
I am feeling much more hopeful than I was even three days ago.
When I get away from this group for too long, even due to increased illness, I start to feel the options are too limited and the conditions too progressed and it feels hopeless. More options become available and I have had difficulty staying updated on my own.
It's so helpful to be reminded there are options and there is hope!

Many thanks to you and to all members here for sharing so openly and for offering mutual support! :grouphug:

To Our Healing!
DejaVu

janieg 01-12-2016 08:58 PM

NIH has granted $4 million to the company UC Davis founded to pursue this SEH inhibitor approach to treating neuropathic pain. :)

http://www.centralvalleybusinesstime.../001/?ID=29766

"Now known as EC5026, the compound is “a potent, orally active and a non-narcotic analgesic that does not adversely affect the brain, gastrointestinal tract, or cardiovascular system,” says Alan Buckpitt, the company's vice president of pharmacology and emeritus professor of molecular biosciences at the UC Davis School of Veterinary Medicine. “The compound effectively treats pain in preclinical models at low oral doses with no apparent adverse or addictive effects. Preclinical studies demonstrate efficacy that exceeds current therapies for diabetic neuropathy.”"

________

Cliffman 01-14-2016 03:25 PM

Quote:

Originally Posted by janieg (Post 1192910)
NIH has granted $4 million to the company UC Davis founded to pursue this SEH inhibitor approach to treating neuropathic pain. :)

http://www.centralvalleybusinesstime.../001/?ID=29766

"Now known as EC5026, the compound is “a potent, orally active and a non-narcotic analgesic that does not adversely affect the brain, gastrointestinal tract, or cardiovascular system,” says Alan Buckpitt, the company's vice president of pharmacology and emeritus professor of molecular biosciences at the UC Davis School of Veterinary Medicine. “The compound effectively treats pain in preclinical models at low oral doses with no apparent adverse or addictive effects. Preclinical studies demonstrate efficacy that exceeds current therapies for diabetic neuropathy.”"

________

If it all works out I wonder how long it will take to get to market?

Cliffman :)

mrsD 01-14-2016 04:56 PM

The mention of "early" clinical trials suggests that the process is just beginning. That means 5+years or more.

Eight 03-11-2016 03:32 PM

Namenda 28 mg at night
Memantine 10 mg 1-3 times per day

Amazing!

Susan g 03-12-2016 02:36 PM

Ran out of nucynta
 
What can I do to control
PN pain

EdmundUK 04-14-2016 02:49 PM

Edmund UK
 
Quote:

Originally Posted by Susan g (Post 1203986)
What can I do to control
PN pain

I also have serious pain in my feet. I have been through all the tests and have had Steriod injections in my toes, Nortons Neurona. No effect, only more pain.
My life has been a complete misery for the last 18 months and I don't think that doctors are very much concerned about the condition. Although I am in my 80s I have been very active, outside every day in all weathers until affected by this. Treatment, Lyrica,two a day and the cream with the very hot chilli. The tablets help but I don't think the cream is helping. I follow these very helpful pages and some of my information I have taken note of and will present it to my consultant. AI hope Susan that you will get some helpful advice as I hope the same! In anticipation, thanks.

EdmundUK 05-22-2016 05:00 PM

EdmundUK
 
My previous post said that I was hoping to present some useful info obtain fron this very useful Forum! After a long wait for the appointment with the consultant at my NH hospital, the biggest waste of my time ever experienced! Full of hope for some sort of info from him to ease my very severe pain in my feet, I struggled to his department only to have less than 4 minutes of his time. After he had been told by his assistant in another room he came in to see me, hand outstretched with the words" I was right then about your condition " He couldn't be anything other than Right the idiot. I had already been sent by him to check for Nortons Neuroma, had the Steriod lnjections. He knew about the results so one doesn't need to be a brain surgeon to sort that one out. I came out of that hospital more that greatly dejected and no further forward in getting any relief. I tried to tell him about a little info from this Forum, B12 , Epsom salts etc, he just did not want to know. Mention the Internet to doctors and they are just not intrested. Sorry to go on so long. Edmund.

EdmundUK 07-01-2016 04:32 PM

PN
 
Quote:

Originally Posted by Joano (Post 1153695)
It looks like they're concentrating on diabetic neuropathy, which I guess is much more common than for people who aren't diabetics--like me!

My PN is now getting quite severe , my Doctor has raised my Lyrica to 100 twice a day. I am also using the hottest chilli cream, forgot the proper name! Had all the tests, I must say that the specialist l saw for a couple of minutes , I felt disgusted, was of no help at all! I wish all PN suffers well.


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