FAQ/Help |
Calendar |
Search |
Today's Posts |
07-10-2015, 11:56 AM | #14 | |||
|
||||
Member
|
Quote:
Interesting to my situation, I've seen estrogen referred to as an "sEH suppressor" in one report (can't drum it up at the moment), but this report seems to indicate the same: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972065/ Estrogen, soluble epoxide hydrolase & cardiovascular injury "17β-estradiol may regulate an emerging novel therapeutic target against CVD – soluble epoxide hydrolase (sEH) . Arachidonic acid is converted to endogenous lipid epoxides epoxy-eicosatrienoic acids (EETs), which sEH (the cytochrome P450 [CYP] eicosanoids-metabolizing enzyme) degrades to 1,2-diols (dihydroxy-eicosatrienoic acids [DHETs]). High sEH levels decrease EETs and increase DHETs, whereas inhibitors of sEH increase the EETs to DHETs ratio in animal models." _______ Last edited by janieg; 07-10-2015 at 04:55 PM. |
|||
Reply With Quote |
|
|
Similar Threads | ||||
Thread | Forum | |||
Neuropathic pain study: Scripps Research Institute | Peripheral Neuropathy | |||
Ms & neuropathic pain | Chronic Pain | |||
Neuropathic Pain | New Member Introductions | |||
Neuropathic Pain | Peripheral Neuropathy | |||
Neuropathic Pain | New Member Introductions |