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Old 09-14-2017, 06:35 PM   #1
janieg
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Default D-Phenylalanine

MrsD,

Do you know anything about this stuff? I read about it somewhere, and decided to give it a shot. I started it on Monday. The jury is still out on whether it's helping my neuropathy as I wax and wane so much, but amazingly, I'm seeing very marked improvement in my lower back which is a misery in its own right.

I've been doing more reading about it, and understand there was some research done a while back that indicates it's particularly helpful for lower back pain. (Not sure why that is, but am still reading.)

Just curious if you have thoughts on it.

janie
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Idiopathic, Full Body, Small Fiber Neuropathy since 11/2013. Symptoms include altered sensation in toes; constant tingling/vibrations in feet and lower legs; intermittent tingling in temples, scalp and face; full body "buzzing" in the morning; referred sensation in feet cause by touch; occasional bouts with severe cramping in my feet and legs; when flaring, full body burning.

Metabolic issues: FBG -90 A1C - 5.3 with glucose spikes over 200, can't metabolize alcohol, high LDL. Genetic mutations contribute to glucose issues.

Current treatments:
  • Omega 3's - Fish Oil (2400 mg EPA, 1200mg DHA), 2000 IU D3, 200 mg Magnesium Threonate,
  • 5 mg Meribin Biotin for low-normal biotinidase levels.
  • Low carb "back to the farm" diet
  • Quell TENS unit, 5% lidocaine patches, magnesium cream
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Old 09-14-2017, 09:54 PM   #2
kiwi33
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D-phenylalanine is the "mirror-image" of L-phenylalanine, which is the form found in proteins and foods. Your body can make L-phenylalanine but can not make D-phenylalanine.

There are couple of reports which suggest that D-phenylalanine may help with chronic pain. They have design flaws which mean that their conclusions are unreliable and no subsequent studies have been reported.

The information here may help you to decide about this http://www.umm.edu/health/medical/al.../phenylalanine.
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Old 09-14-2017, 10:05 PM   #3
janieg
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Yes, I actually saw that link when I was researching. (The Univ. of Maryland is local to me, and I turn to their website quite a bit.)

I'm not one to overreact to things, but difference in my back is just amazing...especially in the morning. I say this as I sit here feeling all the effects of my neuropathy still, which is unfortunate.

We'll see how long it lasts.

Quote:
Originally Posted by kiwi33 View Post
D-phenylalanine is the "mirror-image" of L-phenylalanine, which is the form found in proteins and foods. Your body can make L-phenylalanine but can not make D-phenylalanine.

There are couple of reports which suggest that D-phenylalanine may help with chronic pain. They have design flaws which mean that their conclusions are unreliable and no subsequent studies have been reported.

The information here may help you to decide about this Phenylalanine | University of Maryland Medical Center.
__________________
Idiopathic, Full Body, Small Fiber Neuropathy since 11/2013. Symptoms include altered sensation in toes; constant tingling/vibrations in feet and lower legs; intermittent tingling in temples, scalp and face; full body "buzzing" in the morning; referred sensation in feet cause by touch; occasional bouts with severe cramping in my feet and legs; when flaring, full body burning.

Metabolic issues: FBG -90 A1C - 5.3 with glucose spikes over 200, can't metabolize alcohol, high LDL. Genetic mutations contribute to glucose issues.

Current treatments:
  • Omega 3's - Fish Oil (2400 mg EPA, 1200mg DHA), 2000 IU D3, 200 mg Magnesium Threonate,
  • 5 mg Meribin Biotin for low-normal biotinidase levels.
  • Low carb "back to the farm" diet
  • Quell TENS unit, 5% lidocaine patches, magnesium cream
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