What does it mean if the supplement regimes don't work?
 

Though I have no official dx, I have implemented the supplement regimes for over one year. I have not had any improvement like some have.
I've tried everything with no affect.

Am I just one of the unlucky ones?
Or maybe it's not neuropathy?

Have you tried stopping your supplements? That seems to be a good method to tell if they are doing anything or not. Sometimes it takes stopping them to realize that perhaps they were doing some good.

It all depends on what you are using.

If you use supplements for diabetes... and don't have that, well, don't expect much.

If you are not low in B12, don't expect a supplement to do much.

Many of the supplements are specific to certain actions.

Which ones are you using? and the doses?

Some can be so subtle but still "doing"something positive.

Some can be profound as I have had with grape seed ex and allergy/sinus issues. And edema also. And if it is preventing cancer, it's working.

Some may not do anything, but I like to give a supp a 3 month trial at least. Some may take longer to work in one's system.

I've gone off 2 supps in the last couple yrs and "knew it"...so went back on.

Methyl B12 - 5,000 with folate at 1,000 (1 per day)
Cod Liver Oil - 1,000 2+x day
Co-Q10 - 200mg (1 per day)
ALA & ALC HCI - 600 and 1000 respectively (1 per day)

I've also taken Multi-B Neuropathy support with Benfotiamine 150mg, B2 10mg, B6 10mg, Folic Acid 100mcg, B12 500mcg, B5 50mg but have been taking it more like every second day. Also Vit E, Magnesium L-Threonate50mg plus magnesium lotion at night.

I'm taking all supplements recommended on this site and after months and minths I've haven't noticed a thing! No improvements ....

I think when you don't have a confirmed diagnosis you're gonna have a hard time targeting a specific problem.

Have you kept a journal over time of how the pain is? Video journals are good too.

What I've heard most is Irritated and sensitive nerves. One neuro said "I think" you have pn. I do have Raynauds sporadically and its cousin erthymelagia.

But my feeling is at this point, I have to figure this out myself having visited 20 docs.

Jay Cohen is a doctor who has EM. Three supplements that he uses successfully are Mg, ALA and PC.

http://medicationsense.com/articles/2012/emsup.php

http://www.jaycohenmd.com/erythromelalgia.html

First off, drop that Cod liver oil to one a day. And start taking a good fishoil or krill oil to increase the anti-inflammatory effects of EPA and DHA. (3 reg fish oil or one extra strength krill) Cod liver oil has lots of Vit A in it and should be used cautiously. I don't think you need a B-50 while taking the Neuropathy support. That is too much B6.

600mg of ALA (the old racemic mixed form is not much). You could try the new improved stabilized R-lipoic acid called NaRALA ... just one of those a day is enough. The old form requires about 1800mg a day over time to work. Doctor's Best makes a good affordable Stabilized R-lipoic acid 100mg:
http://www.iherb.com/Doctor-s-Best-B...FUY8gQodXDkL_Q

What brand of CoQ-10 do you use? Is it Qunol or another new solubilized form? 200mg of the older types is not much and is not well absorbed. With Qunol only one a day is needed.

Do you take statin drugs for cholesterol? If so, you will continue with your nerve problems most likely.