If skin Biopsy and Emg are negative.......
 

Doesn't this mean one does not have neuropathy?

Let's start a club!! Both of join first!!! Lol

Yep!
 

We are two of a kind, that's for sure!

And to make things more confusing.......
 

A quote from my neuro yesterday..........

"You have neurological symptoms, for which I can find no neurological cause"

Now, I ask you.....how is one supposed to react to that one?!

Well this is when it gets crazy. My Neuro told me disease can happen else where and create toxins for nerves. Like celiac! Even people with thyroid have these symptoms. So he told me you start investigating other possibilities but it gets crazy.

You are checking Paraneoplastic.

Like for me nephrologist is next as in need to investigate chronic blood in urine without infections.

But, it still can be deficiencies or reaction to some meds.
I know your thought process right now. We are in the same place with this. Going thru things it can be. And it's frustrating. But I am happy there is no real damage. As biopsy and Emg are normal.

Take care

Just a repeat post from another thread--
 

--but one can still get a diagnosis of neuropathy--likely "idiopathic"----if responses to manual nerve testing (which includes pin prick, reflex, and in some cases, monofilament testing), or results on quantitative sensory or abnormal testing (i.e, sudomtor axon reflex test, sweat test, Valsalva maneuver, tilt table) are abnormal. Admittedly, with some of this, one relies on the patient's reports in the absence of "harder, more objective" results.

Then, too, some docs won't give the diagnosis without such "harder, more objective" results.

Could it be Central Nervous System related? Brain and spine? That would not show on emg and nerve fiber biopsy. Something infectious? Thyroid?

If it isn't neuropathy, well then it isn't.....but, there are other things.

Sorry you didn't get answers. I am sure it is frustrating.

Me Too
 

I belong in this club too. Negative EMG & Skin Biopsy. Been told its not neuropathy. Seeing 3rd neuro on Wednesday. I only have the pain, parasthesias, and dysthesias (sp?) and NO sensory loss....rather its sensory overload.

I'm thankful that I don't have any loss of feeling. I hope that it will stay this way. It is a blessing and a positive in this whole thing.

Here's to us and hoping that we will figure this out eventually!

I wonder about no numbness....

When my PN started in my feet, it was mostly pain, then progressed to numbness. In my hands, it was mixed. And when I was pregnant the pain in my hands at night was UNBEARABLE and the OB/GYN sent me to a physiatrist immediately, and I had the EMGs showing 20% function remaining and I had one hand done with a steroid shot, my right hand. I wore the braces 24/7 after that until after delivery.

I always had numbness with both hands and feet, and pain was mixed. Tingling also inbetween when the numbness lifted at times.

depending on how long you have had PN an emg can show up negative because not enough damage has been done yet to show up on that test. If your symptoms continue you might want to repeat that test in another year or so and see if something shows then.

For the skin biopsy as Glenn has posted unless you are within a certain percent tile it is not considered Small fiber neuropathy yet. Again it may take a while to show enough damage to be considered a positive test.

Just something to keep in the back of your mind for the future.

So I not alone
 

Glad I'm not the only one. My Dx is Idiopathic Polyneuropathy, which means many peripheral nerves throughout the body malfunction simultaneously and no one knows why.

Hope it is not CNS......
 

That is why I keep thinking late onset MS (CNS), have read that can also start with abnormal sensory sensations.......scares me.........thinking about visiting an MS specialist, just for peace of mind. I am a professional worrier (I am sure you all noticed!)

One thing that all the Dr.s I've seen told me is that MS is not all over body, it will effect one area at a time. I still insisted on an MRI, but it was negative. But I too have wondered. But with MS there are muscle control issues and alot of people loose vision or have blurred speach as first signs too. Guess yo can always have the MRI to give you peace of mind.

Rose to the rescue again.........
 

Thank you, my Dr. never told me that MS is usually in one area, he just keeps saying, "you don't have MS" (I like reasons). Thank you for that info, makes me feel better.

I like reasons too! Drives my Dr.'s crazy....I ask alot of questions. I think the prefer the paitents who don't ask questions, just take the RX and leave them alone. That is not me! I want real answers! :)

Last couple of times I've been to doctors I show up with notes so I don't forget to ask any of the questions I have. I've also brought print outs of information that I've found to ask questions. You have to be proactive with docs.

Daughter with normal EMG and skin biopsy
 

Ya'll, we are so frustrated and weary. Talked with our newest Pediatric Neuro at Children's National Medical Center after waiting 5 weeks for our child's skin biopsy results. They were normal. She had a normal EMG 2 years ago and 1 year ago. Yet, she has been hospitalized 10 times this past year for severe pain episodes. She has Type 1 diabetes, proximal muscle weakness, ptosis of the eyes, 2 unknown Mitochondrial mutations, a waddling gait, a hand tremor that comes and goes. The Neuro today suggested she is Psychosomatic. Really? She can fake all of the problems and abnormalities. Oh an MRI over a year ago showed "non-specific" white matter changes. Muscle biopsy showed Type 1 muscle fiber hypotrophy and a full body ultra sound showed increased subcutaneous fat and decreased echogenecity. So many, many, many unspecifics. But ya'll can there be that many abnormalities and be Psychosomatic. Ticked me off. Why is it so hard to get help and answers? :confused:

As I read your threads , you see that idiopathic is when doctors doesn't search. If you do all exams then you have the diagnosis..