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-   -   Precise pain relieving cream? (https://www.neurotalk.org/peripheral-neuropathy/131695-precise-pain-relieving-cream.html)

mrsD 09-02-2010 09:11 AM

Precise pain relieving cream?
 
I am on my way out the door to WalMart... and this Precise was on TV... so I looked it up. (new since my vacation, I guess?)
By the makers of Tylenol.

http://www.drugstore.com/qxp277736_3...ving_cream.htm

10% menthol and 30% methyl salicyclate!
This is similar to the new Arthritis patches by Salonpas!

I am going to find this and try it. Might be very good for the feet!

I'll come back to this thread with an evaluation!

antonina 09-02-2010 10:25 AM

I've just started using Prudoxin
 
The new podiatrist prescribed Prudoxin (generic form of Zonalon) which is used primarily for itching but he says it is great for burning/numb feet. Guess what? He's absolutely right! The main ingredient is 5% doxepin hydrochloride and the only side effect listed is "drowsiness," which I haven't noticed as I use it at bedtime.

I think of this as a miracle cream for my achy, burning, numb feet. It costs $30 (my copay) for a small tube but I use a tiny thin film of it.

I'm using Biofreeze for my ankles & calves which are not as painful as my feet.

I look forward to your opinion of the new Tylenol cream. Might be a less expensive replacement for Prudoxin.

mrsD 09-02-2010 11:26 AM

WalMart had it.... for 7.97 for 2.5 oz.

I will try it tonight on my knee and feet and see what happens.

It does look nice to me. The methyl salicylate is very high % and because of that covering large areas would be potentially harmful (like the poor girl who died overusing BenGay recently).

I already use regular Salonpas, with some success, so I am eager to try this cream as well.

Thanks for the Zonalon info. That product came out a long time ago, and never really became popular when I was working.
$30 for a copay for a generic seems steep!

Back many ages ago when I had a severe sciatica attack (working midnights), I used doxepin orally for about 6mos. It worked well that way too. It is a TCA with less side effects than the others. I used 20mg (the antidepressant doses started at 100mg daily).

Online Walgreen's shows they have Precise, but checking by zip code our local store showed out of stock. I called CVS and they did not have it.
But the WalMart by me did, and it did NOT show on their website though. It seems quite new.

JoanB 09-02-2010 11:45 AM

If you google "tylenol precise cream", you will see that there are coupons available for this product at CVS. I'm going to wait for more reviews as I have a cabinet full of topical stuff that hasn't worked for my burning feet. But I sure do hope it turns out to be helpful!

echoes long ago 09-02-2010 12:48 PM

Quote:

Originally Posted by antonina (Post 691145)
The new podiatrist prescribed Prudoxin (generic form of Zonalon) which is used primarily for itching but he says it is great for burning/numb feet. Guess what? He's absolutely right! The main ingredient is 5% doxepin hydrochloride and the only side effect listed is "drowsiness," which I haven't noticed as I use it at bedtime.

I think of this as a miracle cream for my achy, burning, numb feet. It costs $30 (my copay) for a small tube but I use a tiny thin film of it.

I'm using Biofreeze for my ankles & calves which are not as painful as my feet.

I look forward to your opinion of the new Tylenol cream. Might be a less expensive replacement for Prudoxin.


what does it do for the numbness?

mrsD 09-02-2010 01:11 PM

I don't expect much for numbness. But you can never tell.
If the numbness is because the nerves are "dead"... that will be it.

But I have transient numbness in my hands (carpal tunnel) and feet, which comes and goes depending on compression issues.
Too tight shoes =numbness
gripping the steering wheel for long periods and my hands go numb. Some gloves will make my hands numb too.

So for this transient type, perhaps this type is more "inflammatory" etc, and may respond to the Precise.
I have more pain and burning than numbness overall.

The Zonalon might work for numbness since it is a TCA.
I'd try it if I were you, Echoes. I hope you have insurance as it is very expensive (over $100 for 1.5oz generic cash). I would think you'd know something by the end of one tube.

BTW I was checking my WalMart receipt to make sure I got all my bags...you know that spinning gizmo that keeps some of your purchases sometimes????....anyway my Precise cream rang up at 6.97! (the shelf tag was 7.97 and so is the price tag). Don't know why.

mrsD 09-02-2010 02:30 PM

First test spot:
 
I am putting the cream on my poor finger of the right hand which is giving me grief ...I'll show it to the doctor when I go this fall...but I think it is arthritis. (the middle knuckle is swelling a bit and the finger is very stiff some days, like today).

So Today is a good day, as I've had NO Aleve or Tylenol, and it is a small area to test as well. The oral meds might mask or confound any changes in the stiffness of that finger.

First impressions.... This cream is very unlike Biofreeze. There is no cool sensation from the high menthol, and the cream really needs to be rubbed in for at least 2 minutes. It remains a bit greasy for about 15 minutes and then disappears. The cream is quite fluid... more like a thick lotion IMO. It dispenses out of a tiny little hole in the top of the tube. The tube has a flip top and a special blocking plastic barrel which seals off the opening completely. Looks pretty fancy to me in that regard. So there is no unscrewing a cap.

There is a moderate odor of wintergreen, like Salonpas, but it is less than those patches. I can't really smell the menthol at all.

A little seems to go a LONG way. I will do this finger for several days and report back. ;)

antonina 09-02-2010 07:01 PM

Quote:

Originally Posted by echoes long ago (Post 691198)
what does it do for the numbness?

It decreases the numbness and restores some feeling to the soles of my feet. Plus, because the numbness is less, my balance is better as I can actually feel where I am putting my feet. I love love love it.

Sorry if I sound over the top but so far, of all the many creams and potions I've used, this is the best. I wish we could get samples of it so you'd be able to try it without investing big bucks. I found out that the retail price for this is over $120 and that my co pay of $30 is considered "reasonable."

nide44 09-03-2010 08:49 AM

Quote:

Originally Posted by mrsD (Post 691225)
........ There is no cool sensation from the high menthol, and the cream really needs to be rubbed in for at least 2 minutes. It remains a bit greasy for about 15 minutes and then disappears. The cream is quite fluid... more like a thick lotion IMO. It dispenses out of a tiny little hole in the top of the tube. The tube has a flip top ..........

Sounds very similar to my 'Cool Heat'
(generic "Icy Hot" from Rite-Aid)
My 'Cool Heat' becomes more fluid (runny) on hot summer days
and in winter, is more of a cream consistency.

mrsD 09-03-2010 09:54 AM

I used Precise on my right foot and knee last night.

My foot seemed better than the left and I fell asleep quickly.
But there is no "cooling" sensation like with the Biofreeze. I've been having more pain than burning in my feet since coming home. All these stairs, I think.

Today without the cream so far my finger is back to sore/stiff, and everything else seems the same.

It might be that continued use results in longer improvements.

Tonight I'll do both feet and see if that is better.

But there is no real momentous results for me yet that I can report. Biofreeze seems more dramatic, at least for me.

mrsD 09-07-2010 06:08 AM

Now some burning has started!

I have been using the Precise cream on my right side only, so I can compare to my left untreated side.

My left foot has been very rough lately, so I started the cream on it....surprise....significant burning there! However, this morning it appears less swollen. It has been moderately swollen, on the instep for a while now, and I am not looking forward to a doctor visit for it. This is the area when I had surgery 50 yrs ago to remove a cavernous hemagioma tumor that bled all the time.
Today with lasers, it would probably be a much less invasive surgery. At the time, the doctors told me emphatically, NOT to have surgery on it again EVER. Every time I've shown a doctor so far this huge scar and discussed it, I get a very BLANK look.

Now I worry the tumor is growing back under the skin? It is interfering with many shoes I try to wear. I can't wear anything now that hits that scar, as it is very painful. If I try to wear
walking sports shoes, they need a huge padded tongue and I can't lace the shoe over it.

So today it appears the foot is less swollen. And it is still stinging some. I think the swelling is from disrupted lymphatic drainage since it is always better when I lie down, and it goes South if I am on it all day.

The Precise is working best on my right hand with the very stiff finger. And it works some on my knee and right foot.

So far I have mixed results with it. I don't know if it is going to help PNers. It appears to be a moderate intervention for arthritis type pain. With 10% menthol one would think it would work on nerves, but it doesn't seem as effective as Biofreeze is for me at all which is 3.5% menthol.

I did sleep thru the night, last night with no waking. THAT is a definite improvement to note.

Kitt 09-07-2010 09:22 AM

Thanks for the update. I think I will just stick with my Biofreeze.:) But keep us posted as to any new results.

malawigirl08 09-13-2010 04:10 PM

Quote:

Originally Posted by antonina (Post 691145)
The new podiatrist prescribed Prudoxin (generic form of Zonalon) which is used primarily for itching but he says it is great for burning/numb feet. Guess what? He's absolutely right! The main ingredient is 5% doxepin hydrochloride and the only side effect listed is "drowsiness," which I haven't noticed as I use it at bedtime.

I think of this as a miracle cream for my achy, burning, numb feet. It costs $30 (my copay) for a small tube but I use a tiny thin film of it.

I'm using Biofreeze for my ankles & calves which are not as painful as my feet.

I look forward to your opinion of the new Tylenol cream. Might be a less expensive replacement for Prudoxin.

Hi Antonina
I went to my GP and got him to prescribe this cream and am due to start it tonight, I am a little concerned that there is a warning that you should only use for 8 days - have you used this for longer and was it ok?

mrsD 09-13-2010 05:04 PM

Just an update.... I've given up the Precise.

I tried my magnets on my stiff finger, right hand. And they did far more than this cream.

I am disappointed that this product created MORE burning with that high menthol %.... compared to Biofreeze for my feet.

I suppose for some aches and pains it will be "okay". But my magnets worked better in the end. After a week even my hand was tingling and burning..which it never does. So I can't give this cream Precise a blanket endorsement!

I do want to keep track of the doxipen--prudoxin (Zonalon) trials however.

Please make a new thread, preferably on the SubForum above if you have successes. Thanks so much!

antonina 09-13-2010 05:19 PM

Quote:

Originally Posted by malawigirl08 (Post 694682)
Hi Antonina
I went to my GP and got him to prescribe this cream and am due to start it tonight, I am a little concerned that there is a warning that you should only use for 8 days - have you used this for longer and was it ok?

I think using it once p.d. @ bedtime is OK. Perhaps the 8 day time limit may be for folks using it for itching. Since I use a thin film of it on the soles of my feet, I think it'll be fine.

I've not used it every night. Sometimes I alternate w/ Biofreeze. I've used it for a total of 10x. Used it last night and walked a mile (using a rollator) this morning. Feet still hurt but can actually feel the bottoms. I hope it works for you.
Please keep us posted. Good luck!!

malawigirl08 09-14-2010 07:01 PM

Quote:

Originally Posted by antonina (Post 694712)
I think using it once p.d. @ bedtime is OK. Perhaps the 8 day time limit may be for folks using it for itching. Since I use a thin film of it on the soles of my feet, I think it'll be fine.

I've not used it every night. Sometimes I alternate w/ Biofreeze. I've used it for a total of 10x. Used it last night and walked a mile (using a rollator) this morning. Feet still hurt but can actually feel the bottoms. I hope it works for you.
Please keep us posted. Good luck!!

So far so good, last night was great and it knocked me out,I had the best sleep since June when I had my lignacaine infusion.


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