CoQ10... can you tell me about this if you have taken it?
 

Has this helped you? And in what way? I was considering taking it for my reflex sympathetic dystrophy, but is isn't cheap and I was wondering about anyone else's experinces with it. Really looking for someone who has nerve pain/ has taken it and their experience.

Thank you very much!! :winky:

some general info on CoQ10
-
http://www.mayoclinic.com/health/coe...ient=firefox-a

http://www.herbalremedies.com/rsd.html

http://search.store.yahoo.com/cgi-bi...Fx%3FEvxbjwv4n

http://healthlibrary.epnet.com/GetCo...chunkiid=21682

I am not aware of any
 

major studies of CoQ-10 for RSD.

However, for nerve neuropathy, there are studies for L-carnitine and acetyl carnitine.

CoQ-10 is used in high dose for Parkinson's, and some forms of ataxia.

CoQ-10 and carnitine are being used together today in products to prevent
damage and aging to mitochondria in cells. This is a antioxidant approach.

Since CoQ-10 is benign and has little if any negative effects, it certainly can not harm to try. But you would need high doses to get anywhere. I'd use it
with carnitine. Some products are already combined this way.

Both however are expensive, so it is a financial commitment. The PD board has people using high dose CoQ-10... you can ask there where they buy theirs.
I have seen products that claim for best results CoQ-10 and carnitine need some biotin as a helper. The product Juvenon has it added, for example. Biotin is a B vitamin.

There are hints that RSD is a calcium error in the nervous system, and
for a while now bisphosphonates are being tried for it:
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15367305
and this is what pamidronate is:
http://www.drugs.com/MTM/pamidronate.html

The theory is that calcium is over active in the NMDA channels, which are pain
generators. Magnesium counters calcium at the NMDA channel to some extent, and making sure you have enough magnesium may be helpful , but not curative, since RSD is still not fully understood.
http://www.helpforpain.com/arch2001feb.htm

We have a magnesium thread here:
http://neurotalk.psychcentral.com/showthread.php?t=1138

If you choose CoQ-10... choose one that is a soft gel cap with a label
that says it is enhanced absorption.
Powder forms are useless basically. The new Q-sorb and other names are
better. Here is one with a good formulation:
http://www.epic4health.com/noname.html
This supplier also has Carnitine
http://www.epic4health.com/lcar60cap.html
This is the same manufacturer as the Rx Carnitor.
I have used this supplier in the past. They are very good.

I do not recommend taking CoQ10 if you exercise. It has been shown to be very neurotoxic when there is a depletion of oxygen in the brain, which happens when you get out of breath from working out. Will you notice anything overnight? No, but long term... you're risking it.

Quite a long time ago I had extremely bad allergies... my face would swell up and I looked as if I was congenitally malformed... I would be miserable for a month or more in the spring and fall.

During one of those times a lady at the healthfood store told me about CoQ10 and I bought it and tried it.

It worked. I was surprised.

I don't think it was a perfect cure, but it helped a huge amount.

Then a few years later I found that a MegaB taken a few times a day COMPLETELY got rid of my allergies I forgot about CoQ10.

Last year someone on this forum suggested it to me... I forget in what context, so I ordered the 30mg ones, which aren't that expensive, and I take two or three at a time a couple to a few times a day.

I am doing much better, so perhaps they are contributing to that improvement.

I tend to think it's the Whey amino acids that are helping my nerves heal... and the serrapeptase reducing swelling in my back so that there's a lot LOT less back pain... but, I continue to buy and take the CoQ10 because whoever told me about it explained it in such a way that I can see how it could well be contributing to my improvement.

:)

My neuro recommends 300 mgs. of this to help with migraine prevention. My husband's cardiologist recommends 150 mgs. to help with his needs. Overall, I think probably all adults should take the minimum dosage. From what I understand, if you are taking Statin medication (for high cholesterol), it's very important to take CoQ10.

Hi, Ozone.

Where did you learn that?

rose

Hi InHisHands --

It's 3:31 a.m. and I'm awake because I bought the wrong strength of melatonin for me... darn it, I just realized this thread isn't about melatonin...

Well, let me just say that if you are thinking of trying melatonin, the smaller dose is more effective for sleep.

1mg works great for me.

but I accidentally bought the 3mg ones, and it's not working. If I remember correctly the higher dose can act as a stimulent... not what I was hoping for when I took it several hours ago... :(

yah the higher dose messes with ur sleep more than helps. i should know, and if your under 35 id be wary of the melatonin.

but to get back to q10, i would take that as i heard its good for the heart, but ill hafta see about that when mrsd gets back. she seems to be the most informed person on this site, in which i would trust her answers. for me its either mrsd or rose if i want to be informed of something. the exercise thing that ozone said seems to scare me, so for now ill just stick with my b12.

quick reply--
 

I only have a few minutes left here... but I can throw my opinion out quickly...

Our bodies make CoQ-10 daily. I have never heard of this effect of harming
the brain during exercise. In fact CoQ-10 is a free radical quencher that is
helpful "during" exercise.

I will search this out further when I get back, but like rose I'd like some
documentation as to ozone's warning. :confused:

Hi...yes, I've started taking CoQ10 and to my surprise
 

First some related good news...the price of CoQ10 dropped dramatically about a month or two ago...it's about 75% to 80% lower than it used to be! I read about a year ago that a new manufacturing facility was to open in Texas. Apparently it has opened. Before all the CoQ10 was made in Japan.

As a result of the drop in price I decided to increase my dose from 100/200 a day to 400mgs a day to see if it would increase my energy.

Meanwhile, I'd been dealing with nerve pain in my leg due to a fall which had aggravated an old back injury since infancy that included poorly healed broken bones. Since the fall, I often needed a crutch and had great difficulty walking 100 yards.

In fact, I was looking forward to my appointment with the neurosurgeon...that's how bad my situation was.

Well, to my utter surprise, the CoQ10 did a lot more than increase my energy and help me to sleep better. From the very first day the nerve pain in my leg has been reduced greatly. Whereas the burning used to be almost all the time, now it's maybe a half-hour a day, and it's less distracting.

Also I can walk without having to think about every step. I can walk a few hundred yards without a crutch and do it more quickly.

I had no prior inkling that the CoQ10 would help me in this way.

I'm not back to 100%, but I'm postponing the surgery...hopefully forever.

I gave some CoQ10 to a friend who was suffering 24/7 from degenerative back pain down her leg that was made far worse from a physical therapy session.

Again, from the very first day of taking 400 mgs, her pain was greatly reduced. She only takes it intermittently now because she suffers from OCD and too much CoQ10 makes her a little hyper. She's trying 100 mgs but that doesn't seem to be helping her much.

I've read that super high doses of 1,200 mgs has helped Parkinson's patients quite a bit, so there is some evidence that it has a positive effect on nerves.

Also, a pharmacist told me that nerves contain fluid. When the nerves swell, it can cause pain that is untouched by NSAID's and heavy duty pain killers. Well, CoQ10 has been shown to be extremely beneficial for congestive heart failure, which is also a fluid problem.

So maybe the CoQ10 is affecting the nerves in a similar fashion. Maybe it's reducing the fluid swelling inside the nerves.

I don't know for sure. My preliminary Google search hasn't turned up anything other than the original question in this thread.

But it might be something to try for any nerve pain to see whether it would help or not. Remember, it did nothing for me as regards my pain and mobility when I took 100-200 mgs. So a half dose didn't produce a half benefit.

I'd be interested to hear if this works for anyone else. If it does, then this accidental discovery sure could benefit a whole lot of people.

Please let me know.

That is pretty interesting...
 

do you mind sharing with us where you get yours?

They allow that here.

I've always recommended people use as high a dose as they can afford.
And also a quality product. Price has always been a limiting factor.

CoQ-10 works in the mitrochondria of cells to help deliver fatty acids for
conversion to energy. The mitochondria are necessary for all functions in the body, muscles, nerves, everything. When they fail, you fail.

CoQ-10 works in the heart to keep the muscle viable. The fluid accumulation I think is secondary to mito failure and heart failure. Carnitine also works this way, and it is something to consider as well.

I've been looking on the net and see some lowered prices all of a sudden.
That is welcome, since they went UP a couple of years ago.

Thanks for the post... it has info that will help many who read here!

I bought mine at Vitamin World. It's about $15 for 30 softgels of 400 mgs. I broke open a softgel and it was a dark but shiny orange color, which I've read is what it should look like.

The best to you.

Kelley Eidem