NeuroTalk Support Groups

NeuroTalk Support Groups (https://www.neurotalk.org/)

- Vitamins, Nutrients, Herbs and Supplements (https://www.neurotalk.org/vitamins-nutrients-herbs-and-supplements/)

- - Pantethine (https://www.neurotalk.org/vitamins-nutrients-herbs-and-supplements/19587-pantethine.html)

Just read and interesting article about the postive effect of using Pantethine which I guess is a special form of B5. According to the article it's used alot in Japan.

The artcile says its slows down the formation of cholesterol in the liver and boosts burning of fat. It lowers the LDL and raises the HDL. It also lowers triglycerides.

ANyone have any experience with this vitamin, just curious?

Thanks for bringing this to my attention again. I meant to look into it furhter and possibly try it, but I forgot.

Here's a bit from LEF magazine in 2000:

Quote:

Pantothenic acid, also known as vitamin B5, is a little-publicized key nutrient for neuroprotection. Pantothenic acid is converted in our bodies into pantethine, which in turn serves as a substrate for the synthesis of Coenzyme A (CoA). CoA improves brain function by promoting the synthesis of acetylcholine. Metabolites of CoA enhance brain metabolism and energy production through its essential role in the Krebs cycle. The more energy brain cells have, the better they can function in signal transmission, as well as repair themselves and defend against free radicals. Another indirect contribution of pantothenic acid to brain health stems from the fact that CoA improves the metabolism of the heart muscle and lowers serum lipids, thus improving blood flow to the brain. Yet another benefit of pantothenic acid is the increased formation of acetylcholine in the intestines. This intestinal acetylcholine enhances peristalsis (rhythmic intestinal motion), thus preventing constipation and facilitating elimination. Faster peristalsis also means less complete digestion of food, helping prevent obesity.

An increased susceptibility to infections, fatigue and decreased ability to cope with stress could indicate a deficiency of pantothenic acid. This important B vitamin has been shown to help in wound healing, arthritis, building immune antibodies and lowering the toxicity of many antibiotics.

I'll have to look on my bottle of vitamins but is this in B complex or do we need to supplement separately.

The article I read really showed some impressive results in lower triglycerides and bad cholesterol. Apparently docs in Japan prescribe it. Can we get it here?

I have some of this in my vitamin cupboard- look at -
http://www.loweringcholesterol.net/

I need to get back to taking my vits/sup regular again.
I did finally put up my shelf so my vits are right in front of me when I am at the sink now.

I tried this many years ago...

Panthethine had no effect on my blood work. The most significant changes in lipids for me has been fish oil. Lowers triglycerides and raises HDLs.

Everyone is different however.

Pantothenic acid (vitB5) was instrumental in stopping serious brixism that my son once had

Well just wanted to let everyone know my results from my blood tests and since it is cholesterol related this thread was perfect.

From 3/6 to now I have done the following...

Trigylcerdicies 159 to 152 (and thats with adding in some heavy fish oil which I read could affect triglycerides)

HDL 82 to 60 (still good)

LDL...Woo Hoo...202 to 144 All through diet and light exercise. Think of what I can do when I can exercise more. Proved the doc wrong...no need for lipitor yet.

And just for the heck of it...b12 went from 454 to 789...thanks to the sublingual. Thanks for the suggestion, I owe that one to NT.

The one worrisome thing that I did not know if it was cholesterol related was that Cardio CRP??? was high and its said high cardio risk. :eek: But I'll ask doc about it next week.

I will keep at it and see how my cholesterol drops. No pantethine for me yet.

Fish oil has beeen helping people for years. Now Dr.s feel they just
discovered it, May it's because i'm 60 and the longer you live. The more
you notice. This is why Mrs.. D website will be so much help to so many.
Also Rose's site is so helpful. I wish years ago i had remained on fish oil
and B12. I wonder how much Pantethine you should take??:confused:
Sue I just heard after cleaning a sore on your foot,put honey on it. For a
diabectic it will heal sore faster,i hope so. It's been on the news most of
day.

Shelley,

How long have you been on the sublingual B12? That isn't much of an increase unless it has been a very short time or you were very low and malabsorb severely, so will take a longer time to rebuild stores.

How long?

rose

Hi Rose,

I am not sure of the exact date but I would say likely 1 1/2 to 2 months.

Shelley,

Chances are good you were very low, much lower than the first B12 test showed, and that you malabsorb severely.

I hope you will continue with the methylcobalamin and read my website if you haven't already. It won't take long to read, but the basics it discusses are very important for you to understand. It is crucial that you get B12 stores up good and super strong, and keep them strong.

rose

Pantethine is a coenzyme. From what I can remember in chemistry class, coenzymes speed up reactions of other chemicals, but do not do what the main chemicals do. So, left by it self it does nothing. It needs to be with other chemicals to apply its speed of reaction influence. But then, its inflence is not universal either. Other chemicals have to be of a specific group for a coenzyme to do its work.

Note that its inclusion in supplements is only in trace amounts, as in 200 mg. So, my hunch is that, when people say that pentathine works in lowering cholesterol, it is always with other chemicals, and not by itself. For more information, do a google search on "define:coenzyme" (omit quotations). For those who understand chemistry try "define:coenzyme A".

Tom