Anything in between tylenol and oxycodone?
 

I get some relief from the chronic irritation feeling in head and spine from tylenol or advil, but it does not last long. Hesitant to go back on oxy. I know it is a strange question, but never hurts to ask.
Is there anything between tylenol/advil and oxycodone?
I already take large dose of gabapentin. and cymbalta.

Combine Tylenol and aspirin, about 1000 mgs each. My doctor told me to do this. I use it for my bad head aches.

I'd try an ice pack once a day.

Tramadol is an option, and typically given for nerve pain.
It has just gone on control status CIV and some people get habituated on it, but not as much as Benzos or opiates.

Magnesium lotion as I suggested to you before is an amazing thing. You should be using it daily. Morton Epsom Lotion... at WalMart, Walgreen's and online at Amazon.com
A little goes a long way when applied to the neck.

You might not need ANY pain meds using Morton's. It is a miracle thing really.

Indomethacin, naproxin, midrin, I have been on all... I would say Indomethacin is one of the better ones...

for temporary "distraction" pain relief i've used tiger balm

Tramadol however has a warning not to use with SSRI antidepressants.

Thank you everyone. The pain is worst in upper cervical spine and where spine meets brain stem. it is constant. will lotion work for a pain that deep?

thanks for the other suggestions. I will get some aspirin today and see if that combo works. i guess it will be process of elimination

went back on cymbalta from zoloft because the pain was noticably worse without cymbalta. Anybody ever hear of or use savella?

I wouldn't use aspirin without your doctor's
Permission, Markneil. You have Gerd
And take SSRI drugs which can cause bleeding.
You also already take ibuprofen.

That mix can set you up for a major GI
Bleed.

And yes the magnesium works very well
On the neck. The mag is absorbed from the
Lotion and blocks NMDA pain receptors in
The nerves there. Also relaxes tendon
And muscle tension.

Stay away from that aspirin!

I take enteric aspirin. It does not dissolve until it is past the stomach. It takes longer to act because of this but it does not disturb the stomach. I have take 975 mgs daily for 20 years for arthritis in my hands. I tried indomethacin. It made me very confused. I could get lost in a closet.

Some NSAIDs are very lipophic and enter into the brain...
Indomethacin is one. Ketoralac is another.

Indomethacin is well know for causing silent bleeds...it can be very dangerous to take on a regular basis.

That aspirin may be enteric coated, but the major activity of all NSAIDs is systemic. Aspirin and the others will affect clotting and cause bleeding in the brain and anywhere else.

http://www.webmd.com/heart-disease/n...rin-worth-risk

SSRIs increase bleeding risks.
MarkNeil is high risk due to his GI problems, Proton pump inhibitor, etc. So while aspirin is helpful sometimes, it can really cause terrible events--even hemorrhages!

My comment was in response to Gerd and stomach issues. The blood thinning is another issue. I bleed like a stuck pig.

Aspirin and NSAIDs will cause stomach bleeding systemically, not just locally.

It does this by inhibiting the Cox-1 enzyme in fatty acid chemistry.
Cox-1 is responsible for maintaining the mucus coat of the stomach and its integrity from acid. Removing it, leads to
erosions and damage, and ulcers. This is a systemic effect exerted by aspirin in the blood stream affecting the cells lining the stomach. Just like the proton pump inhibitors reduce acid production systemically the same way (not locally on the stomach lining itself). Proton pump inhibitors, are enteric coated to escape stomach acid which deactivates them.

Aspirin also has effects on clotting and platelets. This can encourage a bleed that has started in the stomach, by thinning the blood.

Thank you again for your replies. I dont understand the tremendous pain at brain stem/spine intersection after all these years. The cymbalta and neurontin definitely help. I know it sounds crazy but the pain shoots out from there to arms, shoulderd, face,tailbone...crazy.

markneil, I'm no doctor of course, but did you ever read up about the Thalamic Pain Syndrome and Dejerine-Roussy Syndrome and the types of pain associated with that?
I think you already did that a few times in the past, but just thought I'd remind you. Look up Dysesthesia and see if that makes sense too.

Thanks. I was diagnosed with thalamic syndrome but I didn't think i met the exact criteria. I guess maybe the doctor was right. I will look into the other thing you mentioned. Thanks.

I use a lot of turmeric. The meds are bad for healing, and cause tennitus

for mark

Central Pain Syndrome from NORD
NINDS Central Pain Syndrome Info

Boy, that sure sounds like what I have. I have not been treated with a variety of the drugs mentione and will see neuro to discuss it. Thanks.

Define "regular basis" and where is the bleeding taking place?

I take 6 Indomethacin a day for a total of 150mg a day... I have been for about a month now... how would I know about the bleeds?

Feeling concerned...

http://www.pdrhealth.com/drugs/indocin

http://www.drugcite.com/?q=indomethacin
These numbers seem small because very few people today use indomethacin regularly. Doctors just will not give it. It remains the most dangerous NSAID.

This site give actual statistics for all NSAIDs... but it is from the late 90's...
http://americannutritionassociation..../deadly-nsaids

The drug industry tried to reduce this risk by making Cox-2 types, to spare the Cox-1 effects. But this failed and all but Celebrex were recalled. The Cox-2 blocking types, Vioxx and Bextra created heart attack and stroke, because there is a vital Cox-2 cytokine made in the kidney that dilates blood vessels, (a beneficial effect)....called prostacyclin. Most of the Cox-2 cytokines are involved however in inflammation. So the strong Cox-2 blockers were taken off the market. Celebrex remains, and contains the warnings for heart disease, but it has been a rather weak Cox-2 blocker.

Indomethacin remains for certain types of headache, and for short term (a few days) treatment for gout attacks, but is rarely used today because of its risks. Indocin is given to newborns to close a patent ductus --a blood vessel that is supposed to close on its own after birth. This vessel bypasses the lungs in utero.
http://americannutritionassociation..../deadly-nsaids

However, indomethacin has potentially terrible side effects, and some doctors use alternate NSAIDs for patent ductus.
http://emedicine.medscape.com/articl...nt#aw2aab6b6b2

The brand name Indocin oral form is no longer available in the US. Only generics. This is because of liability factors. It was originally marketed by Merck.

Ahh thank you, ive been taking indomethacin for a little over a month now. 50 mg 3x a day. Dr just upped it to 75mg 3x a day. Got into an argument on phone telling them how it doesnt work for me, and doesnt prevent anything as far as my migraines go and my stabbing headaches. I expressed concern because my bowel patter is very bad now, and I have this weird full feeling in my upper right abdomen. Almost feels like a pulled ab muscle, but its not quite the same feeling. Dr didnt care, said stay on it. Derp, it doesnt help!