Blood work results
 

I recently had blood work to rule a few things out (one being celiac) and the three items below were out of range. My next appointment is not for two months and I am curious if anyone has had a similar result or can help decipher what they could point to.

Immunoglobulin A, Qn, Serum: 554 (Range: 91-414 mg/dL)

Creatine Kinase,Total,Serum: 393 (Range: 24-204 U/L)

Immunofixation Result, Serum:
An apparent polyclonal gammopathy: IgA. Kappa and lambda typing appear increased.

Creatine Kinase is an enzyme found in skeletal and heart muscle. Elevated serum levels of it are a marker for muscle damage. As far as I can see from a PubMed search this has not been linked to Peripheral Neuropathy.

Your IgA (a type of antibody) level is slightly high. Antibodies are made by plasma cells - what "polyclonal" means is that more than one clone of plasma cells is involved in your case. The "kappa and lambda" confirms this. IgA, like all antibodies, is made from H chains (alpha in this case) and L chains (kappa or lambda) - some of your plasma cell clones are making IgA with kappa L chains, others are making IgA with lambda L chains.

Thank you Kiwi.

The neuro sent me to a bone doc who is sending me to a neuromuscular doc. The wait for this is so long as I meanwhile suffer, as many others do. I just want to get better... as many others do.

This looks potentially serious:

http://labtestsonline.org/understand...ight/tab/test/

How long do you have to wait?

Those are my results from the test.

Now I have to see a neuromuscular doc. I was referred to him once before but couldn't get in. It was a 1.5 year wait!

OMG... that is too long. Can you try and find your own doctor?

My doc said that elevated creatinine kinase (CK) implies muscle inflammation which can occur after a strenuous workout (does not apply to me) or a long list of muscle disorders.

I thought the muscles and bones were merely responding to the nerve disorder but maybe not.

Some drugs raise CK levels too, as well as heart damage.

amphotericin B, ampicillin, some anesthetics, blood thinners, aspirin, clofibrate, dexamethasone, furosemide, alcohol, and cocaine, and statins.

This PDF has a longer list of drugs that cause muscle damage:
http://www.charlydmiller.com/LIB05/2004drugRhabdo.pdf

The drugs on that list that would apply are:

Caffeine
Lorazepam

I did fast 12 hours prior to the test if that would make any difference.

I need more than seven minutes with a doctor. It's obviously not a routine diagnosis and so like many others, I have to get in the back of the line at a new doctor and wait my turn, only to be seen for seven minutes again and referred somewhere else, again. It is very frustrating.

Beatle, adding to what mrsD wrote about your antibody levels, can you get your GP to refer you to a specialist clinical immunologist?

A clinical immunologist should be able to interpret those findings better than a GP can and, depending, will be able to recommend further investigations.