Article
 

http://www.upi.com/Health_News/2015/...9741449265570/

Hoping and praying is all I am saying!

Good to know there's something being done for the future. :)

Thanks Baba for posting the article.

Cliffman :hug:

hi there, I am currently being tested for this mutation, my bloodwork got lost last year so I have had to be re-tested for this. It has been found in 30% in people who have idiopathic small fibre neuropathy.

I believe there is a lot of work going into various Nav 1.7 blockers, one of which was convergence, I think they are now getting ready for stage 3 clinical trials:)

I can only imagine the relief people might get with a breakthrough like this. But I do have one concern. People rely on pain to signal a problem and if you eliminate ALL pain, then how would one know if there is a medical problem? Someone might miss the early signs of cancer or other devistating conditions without feeling pain. What might they do about this? Does this only eliminate nerve pain?

What is the exact test please?

Yes. Not having pain might have some disadvantage.
I am not sure about just the nerve pain.

Hi Baba 222, the genetic test is SCN9A - I'm in the UK , they do it is as part of the blood testing for SFN here.

:)

Thank you so much.

Anyone did this here in USA? What is the procedure?

I had 23 and me.
What is the particular SNP?
There are many SCN9A to my raw data.
TIA

Hi baba222

The information in this link lists many of the SNPs in SCN9A which have been associated with perception of pain; http://www.painresearchforum.org/res...rce/5937-scn9a .

Thank you for the article.
I have a list from the SCN9A but cant find the important SNPs. There are about 50 listed in my raw data. I joined 23 and me after the FDA debacle and was trying to figure out my situation before I had to fork out major cash for more lab work.

I hope someone is in the know.

I can also PM my raw data to anyone interested.

TIA

Are you able to post or PM the information about this?

Thank you so much for responding and helping me.

Hi baba222

"I can also PM my raw data to anyone interested."

If you would like to I would be happy to have a look round and see what I can come up with (no promises).

Hi Baba - I had the SCN9A test done in Ohio. The test was after a meeting with a genetic counselor in the neurology dept at OSU who I was referred to by my main neurologist. It was a blood draw here too - they took two vials I believe and then the results were given to me about 8 weeks later (I don't have the mutation so still idiopathic for me) - hope this helps!

Thanks so much. Sounds like I will have to go thru some hoops. Was trying to do it and maybe figure it out on the cheap.

Take care.
:hug:

I sent you a PM.

Thank you so much!

Hi baba222

PM'd you - my impression is that you don't have anything to stress about :).

So what happens if one has this mutation? A little research showed up that it can cause 30% of SFN. So is the idea here (via the article linked to) that finding how to block this mutation will resolve the SFN?

I share the concern re blocking all pain. That could be immensely dangerous for a variety of reasons.