Ocrelizumab
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Yet another miracle drug being rolled out. Maybe this one will be better than the others!
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Ocrelizumab is a humanised monoclonal antibody which blocks the action of a protein called CD20, found on mature B cells. Because of this it is immunosuppressive.
Phase 3 clinical trials of it in the context of MS look very encouraging. It is currently under consideration by the FDA for regulatory approval. There is more about this here; https://www.mssociety.org.uk/ms-rese...ne/ocrelizumab. |
Actually hasn't it been fast-tracked for speedier FDA approval?
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Yes, it is on the "Breakthrough Therapy Designation" list.
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Hearing good things about this stuff. I hope they find it works for SPMS also.
Wouldn't that be nice? |
Today read another promising thing about this, will also ask MS neurosuheon on May 13 John Hopkins doctor, for what that's worth.
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As always, holding my breath, hoping.
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Made it into the Ocrelizumab study
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1week in.....
I got a little light headed in the middle when I got up real fast (real fast is a relative term for me). But it was gone before the treatment was over. I didn't experience even the mild side effects. This alone was a blessing over the "flu like" side effects multiple times a week with Rebif. Next week I get the second half of the first dose. My fingers remain crossed.
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Sally, nice to see/hear from you :)
Hope you are doing ok :hug: Linda |
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This thread was started by Sally last year (3/2016). I saw it and thought she had posted it recently, too! I haven't heard from her but hope she's doing ok. Folks are still talking about the drug Ocrelizumab, though. Hopefully it will be the magic bullet for someone. |
Doggone it ! I did not pay attention to dates, was just excited to see Sally's pic. I so hope Sally is ok..it's been a long time since she posted :(
Does anyone know how Sally is ? Linda |
I just happened to see this. Sally hasn't been doing so well. She's in a nursing home and has been battling pneumonia. In fact I haven't heard from her in a while and am concerned. I'll let her know you were wondering about her.
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Yes please let her know we send our love and healing thoughts....and that she is loved:hug:
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My cousin has PPMS and her neuro has already planned to have her try it...I really hope it works for her. I still want to sit back and wait.. It does have a small incidence of cancers in some patients. I am a DEA daughter and have already survived clear cell carcinoma, so I think I would rather just go without treatment than add to the risk of cancer.
I am already having problems dealing with Rebif after only 1 injection...I am about ready to give up and do without MS meds if my insurance won't let me take Tec again. |
I have a neuro appt on 5/26 and plan to request this med. I'm tired of waiting. I need to be on something.
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Agate - please let Sally know that I say hello too! I hope she is well - pass on well wishes and good thoughts.
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