Benfotiamine
 

Has anyone tried Benfotiamine for their PN?

After being diagnosed, I tried the B12 sublingual for about a year. Blood labs confirmed the B12 regimen in fact raised the level in my body. But, there was no noticeable improvement. Later, a P.A. told me the absolute cure for my numbness would be to take B6. However, Google-search revealed that B6 could actually make the PN worse.

I am willing to experiment further with supplements, just getting a little tired of throwing away $$ on ones that don't work.

I have used this product and not right now...why I'm not sure. I've fallen off taking some of my supplements in the last couple yrs. BUT, like everything we try and use, we are all Unique and Different and what might work for me, may not for you and vice versa....and I find best results with what I've been taking and will have to look at the Thiamine product again. thanks.

Thiamine in large quantities can be very therapeutic for all kinds of neuropathies. It's hard to say if it would work for you, but it's very safe to try. Benfotiamine is good; some would argue that Allithiamine or Lipothiamine are better because they cross the blood-brain barrier, but I've seen success stories from all of these variants.

Yes, I too was thinking on trying the benfotiamine also to see if I can get any benefit . I have also read online about the B-6 and was a little concerned if it can cause more damage. Right now I eat a multi vitamin with B-6 in it at 3MG at 150% DV but I think that is a low dose of it? not sure.

Too much Vitamin B6 can cause problems with your nerves and other side effects.

Kitt

I should start a poll, my PN is primarily numbness, with just occasional nerve lightening bolts. A lot of people suffer mainly from the hot pricks and jabs and other sensory anomalies. I haven't seen much talk, but wonder if anybody ever experiences a reversal of the numbness?

I take B6 in the P5P form....good to do research on these and don't just buy one opinion. I take 50mg nightly and this also helps me get my 8-10 hrs of good REM healing sleep.

What Are the Health Benefits of P5P? | Livestrong.com

OP: Have you considered working with Inosine, I have talked about how it helps my burn/tingle issues.

Mine seems to have progressed with numbness in my feet and calves mostly but have never any type of reversal pretty much steady and slowly growing more numb. Most of my stuff that is bothersome in in the order of sensory problems is with skin burning in a lot of places, muscle movement. Not any jolts or hot pricks but I sure do burn.

I just bought some L-Theanine 250mg (Extra Strength) with Inositol , hoping it will help.

I ordered some Benfotiamine from Amazon,

I looked at this product and it's LOW doses of both...so if I took this one, I'd take 3 daily probably. I buy Inositol that is 500mg caps...and buy Inositol/Choline combo which is 250mg each.

Maybe the L Theanine will work for you but it didn't do much for me yrs back....so I have NOT used it in a long time...good wishes....

Hi tnthomas, Have you found any improvement using this product? And do you know or have you found anymore info. on if it is helpful for p/n or can cause further damage. I guess it could be a problem on the amount you take.

HI Dexter,

As I'm sure you're aware Benfotiamine is a synthetic fat soluble version of B1, Thiamine. We can store it in our liver and use it when needed. Personally I take Benfotiamine every other day and B1 ( water soluble, we can't store it) on the other days simply because Benfotiamine isn't cheap. I can't say whether its helped me because I take it with other supplements, but I believe its essential to take in an anti neuropathy regimen.

I post a link below for a new resource 'Modern Neuropathy.'
Beware, because its a site that's trying to sell products, but it appears to have a lot of information that is useful.


8 Best Supplements for Neuropathy | Modern Neuropathy

Thanks so much Atticus......

I don't know if this is helpful but thought I should post that mrsD posted information about Benfotiamine on a thread called "~~SUPPLEMENTS~~~ for Peripheral Neuropathy:" in the subforum for PN Tips, Resources, Supplements & Other Treatments.

https://www.neurotalk.org/653193-post4.html

Note that it's from 2010 and also note that the Benfotiamine website address she has posted has since changed.

Benfotiamine : Frequently Asked Questions

Thank you, I will look it up...

Sadly, no. But, I am fortunate that the PN hasn't significantly progressed in the past 10 years.

Neuropathy diagnosed in 2017. I also have spreading numbness in feet and moving up, never as far as hips. Early research has me several years on a number of supplements including Benfotiamine. They either aren't working, or i could be so much worse off than I am now. Who knows.
Never seen a reversal but have good days and less good days.
Totally grateful I don't have pain, yet.