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-   -   Interesting....very interesting (https://www.neurotalk.org/survivors-of-suicide/29020-interesting-very-interesting.html)

DocJohn 09-28-2007 01:40 AM

Interesting....very interesting
 
(From Yahoo) HealthDay - THURSDAY, Sept. 27 (HealthDay News) -- Variations in two genesmay help spur suicidal thinking in individuals taking a commonlyprescribed antidepressant, research suggests.

Read the full article...

Alffe 09-28-2007 08:28 AM

Interesting....very interesting
 
http://psychcentral.com/blog/archive...es-discovered/

Curious 09-28-2007 08:41 AM

i pasted it here. don't think doc would mind. if he does....i'll let the fl;ying monkeys out after him. :wink:

Suicidal Genes Discovered

by John M. Grohol, Psy.D.
September 26, 2007
The Oct. 1 issue of The American Journal of Psychiatry will release both a study and editorial suggesting that a set of suicidal gene markers have been discovered. That is, people with these markers have a higher incidence of suicidal thinking (which is often the precursor to suicidal action). This is a significant finding, since there has been little previous evidence that suicidal thoughts or behaviors might be coded all the way down into our genes.
Obviously, genes are not the whole story and environment plays a significant factor into deciding whether we act on a thought, or whether our personality has learned enough resiliency to “go against” such genetic encoding.
Rumor has it that a company will also be marketing a genetic test kit for this set of “suicide markers.”
We’ll post more about this when the study is published on Monday, but thought we’d give a heads-up ahead of time.

Curious 09-28-2007 08:45 AM

i copied doc's headline news post with the link to the full article here. sorry it messed up the sequence...but hey...i have nothing to do with the software. :o it puts posts in the days order.

Alffe 09-28-2007 09:18 AM

LOLOL! So it's a little confusing...so mods make mistakes too. LOLOL!

Curious 09-28-2007 09:51 AM

hehe..just don't go calling the spelling police on me. :D

Lara 09-28-2007 03:13 PM

Thanks for posting that.
Sure makes sense to me and I don't find it one little bit surprising.
I know that the genetic issue hasn't been studied very much but one of our members from the past (sue) got me interested in learning about the genetic influence on suicidal thinking a very long time ago.

Lara 09-28-2007 03:19 PM

http://www.eurekalert.org/pub_releas...-gta092707.php
Genetic test announced for suicidal ideation in patients using antidepressant drugs
Safer prescribing anticipated


Quote:

Boulder, CO, October 1, 2007 – NeuroMark, a Boulder, Colorado company, announced today the immediate availability of a genetic test to identify people at risk of suicidal ideation—thoughts of committing suicide—when prescribed an antidepressant drug. The test, called the Mark-C™ test, is expected to help restore public confidence in antidepressant medication and help to reduce a recently announced spike in suicide rates among U.S. youth. “This is an exciting example of the power of genetics to address a critical need and make important drugs safer for patients worldwide,” stated Kim Bechthold, NeuroMark’s CEO
Watch this space...

http://www.neuromark.com/

Lara 09-28-2007 03:41 PM

I've got to get going but can't get this out of my mind.

Some of the wording in their article above makes me a little sceptical sadly. Good way to sell more antidepressants and more genetic test kits?

hmmnnn, we'll see I guess. It actually doesn't surprise me one bit that there is some genetic trigger that might cause increase in suicidal ideation while taking antidepressants however, I'll remain a sceptic about this one for a while longer I think. I find it a little confusing considering the incredibly horrible experience that some people who have Bipolar Disorder get when they take an SSRI, for example.

Plus, this seems to be only for Celexa / Citalopram isn't it???

Sheesh, and now I have to go . ugh.

Alffe 11-24-2009 08:58 AM

And I wonder what we've learned since then....07...????

Doody 11-24-2009 02:19 PM

But...what about the part about 'a commonly prescribed antidepressant'? I didn't seen in the article anything about that.
Quote:

Originally Posted by DocJohn (Post 152762)
(From Yahoo) HealthDay - THURSDAY, Sept. 27 (HealthDay News) -- Variations in two genesmay help spur suicidal thinking in individuals taking a commonly prescribed antidepressant, research suggests.

Did it say and I'm just not seeing it????? Or are we talking antidepressants in general?

Doody 11-24-2009 02:25 PM

Hmm, I found this article and it addresses antidepressants as well. Maybe that was the reference??? http://www.drugs.com/news/genes-migh...ghts-9466.html

Quote:

There is some evidence that people starting antidepressant medication can develop suicidal ideation, or suicidal thoughts and ideas, although this notion remains controversial.

In 2004, the U.S. Food and Drug Administration (FDA) recommended that the class of drugs known as selective serotonin reuptake inhibitors (SSRIs) carry a strong "black box" warning on the label outlining the possibility of an increase in suicidal ideation. SSRIs include widely used drugs such as Celexa, Paxil, Prozac and Zoloft.

The black box warning was based on studies that found that 4 percent of the group taking SSRIs had suicidal ideation, compared with 2 percent of the group taking a placebo.
And boy howdy, they should include Cymbalta with that group as far as I'm concerned!

mistiis 11-25-2009 01:08 PM

I really find this to be very interesting!! I don't do well on AD's and have dealt with suicidal attempts and ideation since I was a child, and know it is not just due to childhood trauma.


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