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-   -   Australian researchers reveal MS is not a myelin disease (https://www.neurotalk.org/multiple-sclerosis/133842-australian-researchers-reveal-ms-myelin-disease.html)

Koala77 09-27-2010 06:03 PM

Australian researchers reveal MS is not a myelin disease
 
Australian scientists have released a study in which they say MS is not a myelin disease. Rather their research implicates a particular brain cell, the astrocyte.

Have a look at this article and see for yourself.

http://www.msra.org.au/nmo-discovery

In a nutshell, the article is saying that one version of MS, NMO (or neuromyelitis optica), affects the optic nerve and spinal canal. How many of us have had optic neuritis? How many have had problems with their arms, legs, bladder, bowels?

Studies of that version (NMO) have shown the destruction of a certain brain cell (the astrocyte) because it's missing one of the key components. That component is named AQP4.

"If we can measure in MS and NMO patients their level of antibodies against AQP4 there may be a possibility to have a diagnosis of people who might likely develop NMO and MS very early."

The article goes on to say :

"The fact that the immediate cause of the demyelination is the same in both NMO and MS, this discovery is the strongest evidence to date to suggest that demyelination is secondary (not the cause) of MS."


If we believe this article, then the study opens up the potential for treatment to prevent MS, rather than treatment to cure the disease once a person has been afflicted.

Yes... very encouraging.

Debbie D 09-27-2010 08:20 PM

It'll be interesting to see how this information is received by the U.S. neurologic community...
thanks for bringing this here...

SallyC 09-27-2010 08:54 PM

Thanks Koala, the more facts we have, the closer we get.:)

:hug:

PolarExpress 09-27-2010 11:02 PM

That's an interesting take on it. I look forward to hearing what more they learn from this. Thanks for the info, Anne!

Judy2 09-28-2010 03:56 AM

Thanks for posting this info, Koala. With research coming at this miserable disease from different perspectives, hopefully the mystery will be unlocked soon. :)

lefthanded 09-28-2010 04:23 AM

I too will be interested in what my own MS doc thinks of this. I have often wondered why symptoms are often seen as the disease, and not side-effects of the disease process.

Aarcyn 09-28-2010 05:19 PM

Thanks Koala. I don't know if the neurological doctors are thrilled with these kinds of studies. I found my MS doctor to be unreceptive.

Lady 09-29-2010 12:50 AM

Thanks, good find Anne. :)

First they say it's autoimmune, then it's inflammatory, now it may not be myelin. No wonder we get dizzy. I hope they get their heads together and figure this one out, maybe lead to ..something. :hug:

Dejibo 09-29-2010 07:02 AM

My MS MDs say DONT listen to all the blah blah blah studies that come down the pike. Wait for them to prove themselves, and then perk up your ears. If you pay attention to every bit of information that comes down the pike you will make yourself crazy.

Kitty 09-29-2010 11:22 AM

I think they're just trying to confuse us all enough so maybe we won't notice that they're using us as guinea pigs in their own research! :rolleyes: :mad:


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