Alpha Lipoic Acid and Liver health
 

http://www.naturalnews.com/024513.html

(NaturalNews) Even though the liver is not pretty, it is an extremely important organ that has a month-long health observance in October named after it by the American Liver Foundation (www.liverfoundation.org), called Liver Awareness Month. Reasons to appreciate our liver abound since this organ does all of the following, and more: saves up energy; makes bile to help break down food; keeps pollution from hurting us; stops cuts from bleeding too long; kills germs; gets rid of toxic chemicals; and helps build muscle. According to the foundation, liver disease affects one in 10 Americans, or about 30 million people -- including children.Liver disease begins with inflammation. If left untreated, especially over time, inflamed liver tissue begins to scar or become fibrous, a condition known as fibrosis. If fibrosis is not treated or healed, irreversible damage can occur, called cirrhosis; this can lead to liver cancer. If the liver loses most or all of its function, a life-threatening condition called liver failure can result.To complicate matters further, there is also hepatitis C, a disease of the liver caused by the hepatitis C virus, or HCV. Although it is fortunate that 15 to 40 percent of people who contract HCV are able to successfully fight off the virus within the first six months, sadly most of the patients who are not able to beat the virus wind up developing a long-term, chronic hepatitis C infection.Over 4 million Americans have been infected with hepatitis C and the virus is responsible for 8,000 to 10,000 deaths annually. This is one of the most common reasons for liver transplants.Alpha Lipoic Acid
One nutrient that has been the focus of related research and which shows the greatest promise for liver health has curiously not yet attained the level of popularity enjoyed by milk thistle; it is: alpha lipoic acid.Alpha lipoic acid (or ALA) was discovered by University of Illinois enzymologist Irwin Gunsalus in 1948 and described and characterized by University of Texas biochemist Lester J. Reed in March 1951.It is a natural substance that, according to ALA pioneer Burt Berkson, M.D., in the December 2007 edition of the Townsend Letter, is the "rate-limiting factor for the production of energy from carbohydrates." In other words, without alpha lipoic acid we could not obtain energy from the food we eat and we could not stay alive.The first large-scale human clinical studies using alpha lipoic acid in the U.S. were carried out in the 1970s by Berkson, Frederick C. Bartter, M.D., and other scientists at the National Institutes of Health (NIH). The researchers gave the nutrient to 79 people with severe liver damage; 75 of those, according to Berkson, recovered full liver function.More recently, in 1999 Berkson published three case reports using a triple-antioxidant supplement regimen in patients with liver disease, including chronic hepatitis C infection. After several months of treatment with a combination of alpha lipoic acid, selenium and silymarin, all three patients recovered most or all of their liver function, avoided liver transplantation and went on to live healthy, productive lives free of the symptoms of liver disease.From 2006 to 2008, studies in humans and animals have shown that alpha lipoic acid can provide important improvements in the following: recovery following liver surgery; protection from chemotherapy side effects and chemical poisoning; liver regeneration; and protection against liver and kidney damage from acetaminophen-containing drugs (e.g., Tylenol, Anacin-3 and Percocet).Since acetaminophen poisoning sends over 56,000 people to emergency rooms each year in the U.S., these study results are all the more impressive.Additionally, alpha lipoic acid also helps in the areas of nerve health (e.g., diabetic neuropathy), metabolic health (e.g., insulin resistance and weight control) and brain health.In an industrialized world heavily burdened by pollution and toxic chemicals, alpha lipoic acid has emerged, and rightly so, as a nutritional ray of hope for many.References

This is very interesting...
 

Many of us at PN use lipoic acid.

Readers here should know that there is one study on rats showing high dose alpha lipoic may suppress thyroid function.
I searched that about a year ago and could not find other articles on it or concerning human use. One of our members here asked her doctor, who had no answer or comment, about this potential.

Regular alpha lipoic contains two isomers, only one of which is active in the body. There is a purified form called r-lipoic that is used in lower doses, and works quite well for metabolic issues and nerve pain so far for us.

I used Alpha years ago with no results. But I like the r-lipoic very much and use 100mg a day.

Thanks for posting this information, Shelley!

The article about ALA and liver health is very interesting. I have some questions about ALA. I am currently on it. I have not been able to get R lipoic acid. Do you think i can get it in GNC or Sam's club? I find it very hard to find most supplements in my country. I have had to ask friends qho come and go to the US to get me some, but right now i am not on that possibility.

I currently take on pill of ALA a day, is that too much?? Is that a megadose? I am concerned about ALA affecting thyroid function, since i have hypothiroidism.

there is only that one study...
 

so I don't think that is much to go on regarding thyroid.

What dose of ALA do you take?
Odd that iherb doesn't ship to Mexico!

I doubt you could have a toxic reaction to one cap of ALA.

Thank you!