Sinemet not always working
 

I've been stable since being first diagnosed 9 years ago. During that time I have not needed to change (or increase) my medication. I've been taking 1.5 mg of Mirapex three times a day and 2 mg of Artane twice a day. I'm now on the bubble of having to change medications.

The doctor is giving me three months to see if exercise will help (in addition to Parkinson's I also have severe scoliosis) at which time he'll increase my Mirapex to 2 mg. three times a day. After that, the obvious solution is to try Sinemet.


My neurologist is reluctant to start me on Sinemet for several reasons. First I suspect that he's still in denial that I even have Parkinson's. This is because I was diagnosed back in Texas, have been medicated ever since, and quite honestly he has never seen me off medication

While I can accept that, he also said that Sinemet doesn't work for everyone???? That statement totally stumped me as I don't recall anyone posting that Sinemet doesn't help.

Could anyone enlighten me if this is the case. I'd really like some insight.

[While I can accept that, he also said that Sinemet doesn't work for everyone???? That statement totally stumped me as I don't recall anyone posting that Sinemet doesn't help.

Could anyone enlighten me if this is the case. I'd really like some insight.]

For 8 years I have had most of the classic pd symptoms as well as a diagnosis of pd from five different neurologists/MDS. Been on and off sinemet for 4 years (and most recently sinemet and requip). Haven't noticed any effects positive or negative other than mild nausea and sleepiness, but definitely no offs or ons. Would be delighted to find something that provided some symptomatic relief. So far it hasn't been carbidopa/levodopa. There must be certain non-dopamine responsive forms of this idiosyncratic condition.

Mirapex and Artane
 

I've been symptom free for 9 years taking Mirapex (1.5 mg 3 times a day) and Artane (2 mg twice a day). You might want to try it.