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-   -   Some hope on the horizon (https://www.neurotalk.org/pn-tips-resources-supplements-and-other-treatments/226949-hope-horizon.html)

Teals1 10-04-2015 07:34 PM

Some hope on the horizon
 
Has anyone heard of the clinical trials that are to start in Switzerland for Atexakin Slfa as the first disease modifying drug for neuropathic? Hoping to reduce pain, improve nerve conductivity and nerve regeneration. Does sound a little too good to be true - but we can hope.
Relief Theraputics are the company licences to start clinical trials

EnglishDave 10-05-2015 09:06 AM

Here is a Link to a short article:

http://www.pharmaceutical-technology...atment-4665940

Dave.

ger715 10-05-2015 11:24 AM

Quote:

Originally Posted by EnglishDave (Post 1175646)
Here is a Link to a short article:

http://www.pharmaceutical-technology...atment-4665940

Dave.


Sounds promising.


Gerry

mrsD 10-05-2015 11:47 AM

Looks good to me, and it already has passed other studies which means it may not be long coming to us finally.

Patrick Winter 10-05-2015 12:10 PM

Quote:

Originally Posted by mrsd (Post 1175680)
looks good to me, and it already has passed other studies which means it may not be long coming to us finally.

line forms behind me! That said, it looks like this may not be helpful to small fiber neuropathy sufferers or those with axon damage. Unless I am reading it wrong?

nilram 11-29-2015 07:58 PM

Quote:

Originally Posted by Patrick Winter (Post 1175690)
line forms behind me! That said, it looks like this may not be helpful to small fiber neuropathy sufferers or those with axon damage. Unless I am reading it wrong?

Diabetic neuropathy is a form of small-fiber nerve damage, and they're also somewhat general in their statement ("associated with neuropathies") so I'm thinking this will have general use. Adding bold & italic to the bits I think are especially cool --

Quote:

The company noted that atexakin alfa has the potential of relieving pain, as well as non-pain symptoms associated with neuropathies by restoring normal innervation in the periphery.

Patrick Winter 11-30-2015 01:24 PM

Quote:

Originally Posted by mrsD (Post 1175680)
Looks good to me, and it already has passed other studies which means it may not be long coming to us finally.

and I'm sure the insurance companies will eagerly completely cover these no problem <sarc>

madisongrrl 11-30-2015 08:54 PM

http://neurotalk.psychcentral.com/thread228927.html

madisongrrl 11-30-2015 10:35 PM

After reading the press release a bit closer, it appears that they have yet to even start Phase II trials - "Relief will engage in clinical development to evaluate the therapeutic efficacy of atexakin alfa...."

In Phase II and III, it is not uncommon to have 6 month delay to even get the trial started. The average Phase III trial lasts over 2 years, give or take - depending on the indication. And that is just the trial time. That doesn't include all the stats, analysis, write up, review, and FDA filing etc.

I'm probably less interested in this knowing that it is a Disease Modifying Drug and will probably have a significant side effect profile. However, I will keep one eye on this one....

missiviky 08-09-2016 05:39 AM

Atexakin studies
 
Does anyone know at this time the status of the studies of Atexakin.


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