More evidence of a link between systemic inflammation and Parkinson's disease
"... the incidence of PD was 78% lower in patients with IBD who received anti-TNF therapy compared with those who did not ..."
"These findings support a role of systemic inflammation in the development of both PD and IBD ..." Medscape article: Old Drug May Get New Life in Parkinson's Prevention. Medscape: Medscape Access EurekAlert article: Parkinson's disease among patients with inflammatory bowel disease. Parkinson's disease among patients with inflammatory bowel disease | EurekAlert! Science News Research paper (not open access, only "Key Points" and "Abstract" are accessible): Anti-Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease, Inga Peter et al., JAMA Neurol. Published online April 23, 2018. doi:10.1001/jamaneurol.2018.0605. Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease | Gastroenterology | JAMA Neurology | JAMA Network Editorial (not open access, only first page is accessible): Discovering New Benefits From Old Drugs With Big Data - Promise for Parkinson Disease, Abby Olsen et al., JAMA Neurol. Published online April 23, 2018. doi:10.1001/jamaneurol.2018.0345. Discovering New Benefits From Old Drugs With Big Data—Promise for Parkinson Disease | Gastroenterology | JAMA Neurology | JAMA Network Although the research paper and the editorial are not open access, I found the bits that were accessible to be of interest. |
Update
I've just noticed that the SoPD blog has done a substantial post on this topic.
IBD+TNF AB ≠ PD? | The Science of Parkinson's |
Thanks jeffreyn - interesting and potentially very promising.
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More articles
A few other websites have now written articles covering this research paper. I found the following articles to be of interest, particularly as they include expert commentary from independent researchers.
AlzForum article: Treat IBD, Dodge PD? Epidemiology Ties Parkinson’s to Inflammation. Treat IBD, Dodge PD? Epidemiology Ties Parkinson’s to Inflammation | ALZFORUM MEDPAGE TODAY article: Anti-TNF Cuts PD Risk in IBD Anti-TNF Cuts PD Risk in IBD | Medpage Today MANAGED HEALTH CARE CONNECT article: IBD Patients Treated With Anti-TNF Drugs Have a Lower Risk of Parkinson’s https://www.managedhealthcareconnect...sk-parkinson-s |
I wonder if IV glutathione would help prevent PD. Also, what about non-steroidal anti-inflammatory drugs like Aleve. I guess I am asking whether any kind of anti-inflammatory would be of interest.
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More evidence of a link between IBD and PD
"Corticosteroid and anti-TNF use may prevent PD in patients with IBD."
Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson's Disease: A South Korean Nationwide Population-Based Study (2019): Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson's Disease: A South Korean Nationwide Population-Based Study. - PubMed - NCBI |
Curcumin
If I had Parkinson's, I would be taking 1 gram or more of curcumin.
Emerging Role of Curcumin in Parkinsons Disease | OMICS International curcumin parkinson's - Google Search |
L serine
[QUOTE=ashleyk;1279090]If I had Parkinson's, I would be taking 1 gram or more of curcumin.
has anyone checked out l serine? that is L serine |
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