Pramipexole & Depression....Mitochondria
 

Pramipexole Successfully Treats Depressive and Motor Symptoms
Medscape

May 11, 2010 — The dopamine agonist pramipexole improves depressive symptoms in patients with Parkinson's disease (PD), according to results of a new ...


Cells Prevented From Destroying Defective Mitochondria By Mutations That Cause Parkinson's Disease

Medical News Today Tue, 11 May 2010 08:34 AM PDT

Mutations that cause Parkinson's disease prevent cells from destroying defective mitochondria, according to a study published online May 10 in the Journal of Cell Biology. Defects in the ubiquitin ligase Parkin are linked to early-onset cases of this neurodegenerative disorder. The wild-type protein promotes the removal of impaired mitochondria by a specialized version of the autophagy pathway ...