Article
 

http://lib.bioinfo.pl/auth:Oaklander,AL

Pain. 2006 Apr 3;: 16600507
Patients with Ehlers Danlos syndrome and CRPS: A possible association?
[My paper] Joan M Stoler , Anne Louise Oaklander
Rare patients are left with chronic pain, vasodysregulation, and other symptoms that define complex regional pain syndrome (CRPS), after limb traumas. The predisposing factors are unknown. Genetic factors undoubtedly contribute, but have not yet been identified. We report four CRPS patients also diagnosed with the classical or hypermobility forms of Ehlers Danlos syndrome (EDS), inherited disorders of connective tissue. These patients had been diagnosed using standard diagnostic criteria for CRPS and for EDS. All had sustained joint injury; in three this had been surgically treated. The association of these two diagnoses leads us to hypothesize that EDS might contribute to the development of CRPS in one or more of the following ways: via stretch injury to nerves traversing hypermobile joints, increased fragility of nerve connective tissue, or nerve trauma from more frequent surgery. We review the clinical presentation of the different Ehlers Danlos syndromes and provide clinical criteria that can be used to screen CRPS patients for EDS for clinical or research purposes.

Hey buckwheat - Is there a more updated article on this - The link provided is for an article from 2002 - Just wondering if they did more research on this...

Hi Their,
The article is from 2006.

The Postherpetic neuralgia article is 2002.

Hugs, Roz

Thanks, Roz,
Nice to see you here, missed you! It's just this kind of research that might possibly give some clues to the triggering of RSD, interesting. Thanks also for the website link, I haven't visited it before, it has a good, clean layout, easy to read and very clear,
all the best :)

I wonder how many RSD members here may have hypermobility?

a link for a "test" for it-
http://hypermobility.org/beighton.php

I'll start a new thread and ask about this too.

Patients with Ehlers Danlos syndrome and CRPS: A Possible Association?
 

Here's a copy of the article. For personal, non-commercial use only, please.

Also, before anyone trips out too much on the issue of hypermobile joints (I can produce the sound of one hand clapping myself), check out Figure 1 in the article for an example of what the authors are referring to. Ouch!

Mike

Hi Jo,
The problem with that test is their are several different types of Ehlers Danlos syndromes. If this is the root of my problem I would probally be the vascular type.:mad:

When I was young I was very mobile. Not today.

I always loved sports and was very active before my injury. The day before RSD I had run a couple miles. I have stated before I was like a bunny that never stopped.

Big Hugs, Roz

Bumping up. Folks, please take a look at the full text .pdf file of the article, which I posted in this thread a couple of days ago. So far, only one person has checked it out.

Thanks.

Mike

Hi Mike,
Thanks so much for the full article. I have read it. Hugs, Roz