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-   -   For anyone taking neurontin (https://www.neurotalk.org/peripheral-neuropathy/16475-taking-neurontin.html)

Lily 03-28-2007 01:53 PM

For anyone taking neurontin
 
If you have been given neurontin, or another anti-seizure drug for neuropathy, just be aware that they can interfere with vitamin B absorption. I was on neurontin for a long time and ended up with alot of problems because I was never told that. The drug can actually over time exacerbate the PN you had to begin with because it depletes your B. Now I research carefully every drug I take.

glenntaj 03-28-2007 03:58 PM

Very true.
 
It's part of the reason I advise anybody on anti-seizure meds, many of which, like Neurontin, are dealt with by the kidneys rather than being metabolized by the liver, to take vitamin B supplements, including seperate B-12, and NOT to take them around the time of the med doses.

The flushing action of the meds on the kidneys tends to make it harder for b-vitmains to stay in the body long enough to be absorbed, so it is best to take them in goodly amounts. I take approximately 50mg a day of most of the B's, 800mg folic acid, and an additional sublingual 2000mcg/day of methylcobalamin B12, which is particularly hard to absorb when there is any medication interference.

Oh_Breeze 04-09-2007 11:27 PM

Thankyou both very much...
 
for this information as I just began taking Neurontin 3 weeks ago prescribed to me for diabetic neuropathy!

Lisa

mrsD 04-10-2007 04:51 AM

I could not find documentation for this interaction.
 
I did find that some websites, lump ALL anticonvulsants together when
discussing nutrients. Gabapentin may work the same way as those others.

for example this one:
http://www.evitamins.com/healthnotes...tentID=1390003

Notice how generalized and non-specific the data are.

Until I see studies specifically for gabapentin, I would be cautious interpreting
these websites. (no studies come up on PubMed for gabapentin).

Neither of the references I use, show any data for gabapentin specifically.


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