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-   -   levodopa - Intec records Parkinson's clinical trial success The number of pills requi (https://www.neurotalk.org/parkinson-s-disease/131537-levodopa-intec-records-parkinsons-clinical-trial-success-pills-requi.html)

soccertese 08-31-2010 02:28 PM

levodopa - Intec records Parkinson's clinical trial success The number of pills requi
 
http://www.globes.co.il/serveen/glob...85348&fid=1725
http://www.intecpharma.com/levodopa-...s-disease.html

"Both of these phenomena are believed to be a result of the pulsatile stimulation of striatal dopamine receptors, caused by fluctuations in Levodopa blood concentrations between doses. To date, a satisfactory sustained-release formulation of Levodopa has not been possible because LD is absorbed mainly in the upper intestines and a slow release product that has passed the area of absorption is not effective. "
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does that explain why CR is so unpredictable, at least for me?


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