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-   -   etanercept (https://www.neurotalk.org/traumatic-brain-injury-and-post-concussion-syndrome/236222-etanercept.html)

Ozziejane 05-24-2016 10:18 PM

etanercept
 
has anyone any experience with this drug for hypoxic brain injury? Ive been doing some reading about a recent success in Qld and a trial thats planned in Australia.

kiwi33 05-25-2016 12:04 AM

The Australian clinical trial that you mentioned is outlined here; Alzheimer's trial - Griffith University

It is confined to elderly subjects with late-onset Alzheimer’s Disease. Depending on its results, Etanercept might get regulatory approval here for treatment of Alzheimer’s Disease but I don't know about its possible role in treating hypoxic brain injury.

Ozziejane 05-25-2016 02:54 AM

Its already being used as a stroke treatment in a Florida clinic and the medical trials seem promising. Thanks for the link to the trial. I emailed the USA clinic and received a very quick return call, with an offer of a $USD 500 phone consultation. Think I will cool my heels and do more research first as the treatment is about $USD7000 per injection, plus travel and accomodation. The side effects include immune suppression. Any one else know anything?

kiwi33 05-25-2016 03:48 AM

I don't know if the "Florida clinic" that you refer to is the "Institute of Neurological Recovery" (Boca Raton, FL Office | Institute of Neurological Recovery).

If so, I would be very cautious about it - Dr Tobinick has several such entities.

In my view he makes a number of unsupported claims about the alleged benefits of Enbrel/Etanercept for a wide range of neurological conditions and charges a lot for this alleged therapy.

You may find this commentary helpful in this context; Enbrel for Stroke and Alzheimer’s << Science-Based Medicine.

Mark in Idaho 05-27-2016 11:40 PM

Amantadine has been used in some cases and shown benefit. It does not have broad use.


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