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The ketogenic diet may have mood-stabilizing properties.

Med Hypotheses. 2001 Dec;57(6):724-6.
The ketogenic diet may have mood-stabilizing properties.

El-Mallakh RS,
Paskitti ME.
Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Kentucky 40292, USA.

Quote:

The ketogenic diet, originally introduced in the 1920s, has been undergoing a recent resurgence as an adjunctive treatment for refractory epilepsy, particularly in children. In this difficult-to-treat population, the diet exhibits remarkable efficacy with two-thirds showing significant reduction in seizure frequency and one-third becoming nearly seizure-free.

There are several reasons to suspect that the ketogenic diet may also have utility as a mood stabilizer in bipolar illness. These include the observation that several anticonvulsant interventions may improve outcome in mood disorders.

Furthermore, beneficial changes in brain-energy profile are noted in subjects on the ketogenic diet. This is important since global cerebral hypometabolism is a characteristic of the brains of depressed or manic individuals.

Finally, the extracellular changes that occur in ketosis would be expected to decrease intracellular sodium concentrations, a common property of all effective mood stabilizers.

Trials of the ketogenic diet in relapse prevention of bipolar mood episodes are warranted.

I have not goggle ketogenic but is that a high protein diet?
bizi

Hi,
It's a high fat diet. 80-90% of the calories are from fat. Cheese cake is allowed I think.
I would not try to reach ketosis without a doctor.
Mari

http://www.epilepsy.org.uk/info/ketogenic.html

Quote:

The ketogenic diet is a high fat, adequate protein, low carbohydrate diet designed to mimic many of the biochemical changes associated with prolonged starvation.

http://www.ttuhsc.edu/som/FamMed/dietcomp.jpg -- pie chart of the diet

http://www.ttuhsc.edu/som/fammed/ketogenic.html

Quote:

Originally Posted by bizi (Post 71945)

like eskimos!

Hi, Bizi. I think perhaps the Inuit and others eating traditional food diets, just might have the right idea. I really liked your post. Thank you. :)

There is a lovely post at the blog connected to the Failsafe Diet site at wordpress about on GABA. The blog is called "autoimmunethyroid" at wordpress.

Chocolate was everything that came to my mind... :rolleyes:

yaaaaaaaaaaaaaaaaaaaaa

chocolate mousse
chocolate frappé
chocolate fudge
chocolate cake
chocolate brownies
chocolate liqueur (allowed?)

white chocolate
dark chocolate
every-shade-in-between chocolate
chocolate covered raisins
chocolate eclairs
a divine dove dark bar

chocolate-chip chocolate cookies mmmmm maybe by keebler?
cococoCOcoa-puffs
chocolate rice krispies
moccaccino
chocolate-filled croissant
chocolate frostingg..... by the spoon....
double chocolate chip chocolate ice cream

nutella.... chocolate flavored hazelnut butter

i should stop now. :o i can already feel the calories... or chocaries

and maybe this explains cheese cravings too.

not gonna go there.

still looking for better science

Hi,
Every six months or so, I check google scholar for updated publications about this diet for bipolar. I get nothing.

Intuitively, it seems that the ketogenic diet would work on mood, anxiety, and so on.

I'm willing to bet that we will see some good science at some point --especially as the diet is being readapted into the epilepsy community.

M.

Quote:

Originally Posted by waves (Post 735507)

nutella.... chocolate flavored hazelnut butter

i should stop now. :o i can already feel the calories... or chocaries

Oh Dear!

Waves, Nutella is positively addicting!
I don't know how people can keep it in the house!

M.